Description |
checkpoint with forkhead and ring finger domains |
growth factor receptor bound protein 14 |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Cognitive function ( 24684796)
- Height ( 31562340)
- Mean corpuscular hemoglobin ( 32888494)
- Mean corpuscular volume ( 32888494)
- Refractive error ( 32231278)
- Smoking initiation (ever regular vs never regular) ( 30679032)
- Smoking status (ever vs never smokers) ( 30643258)
- Systolic blood pressure x quantitative lifestyle risk score interaction (1df test) ( 32227373)
- Systolic blood pressure x quantitative lifestyle risk score interaction (2df test) ( 32227373)
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- Adventurousness ( 30643258)
- Blood pressure ( 24954895 21572416)
- Body fat percentage ( 26833246 31453325)
- Body fat percentage variance ( 31453325)
- Body mass index ( 29381148 26426971)
- Body mass index (age>50) ( 26426971)
- Body mass index x sex x age interaction (4df test) ( 26426971)
- Body shape index ( 34021172)
- Coronary artery disease ( 32469254 33020668)
- Diastolic blood pressure ( 28739976 27618452)
- Diastolic blood pressure (cigarette smoking interaction) ( 29455858)
- Diastolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
- Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
- Fasting blood insulin ( 25631608)
- Fasting blood insulin (BMI interaction) ( 22581228)
- Fasting insulin ( 33402679)
- Glomerular filtration rate in chronic kidney disease ( 26420894)
- Glycine levels ( 30837465)
- HDL cholesterol levels ( 30698716)
- HDL cholesterol levels in current drinkers ( 30698716)
- HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
- HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
- High density lipoprotein cholesterol levels ( 33339817)
- Hip circumference ( 25673412)
- Hip circumference adjusted for BMI ( 25673412)
- Hip index ( 34021172)
- Hypertension ( 30487518)
- Immunoglobulin A vasculitis ( 28698626)
- LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
- Mean arterial pressure ( 29403010 30487518)
- Mean arterial pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
- Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962)
- Myocardial infarction ( 33532862)
- Number of sexual partners ( 30643258)
- Perceived sweetness of sucrose ( 31005972)
- Pulse pressure ( 27841878 28739976 30487518)
- Pulse pressure x alcohol consumption interaction (2df test) ( 29912962)
- Response to statin therapy ( 20339536)
- Sexual dimorphism in anthropometric traits ( 23754948)
- Systolic blood pressure ( 26390057 28135244 27841878 29403010 28739976 27618447 27618452)
- Systolic blood pressure (cigarette smoking interaction) ( 29455858)
- Systolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
- Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
- Triglyceride levels ( 32203549 30698716)
- Triglyceride levels in current drinkers ( 30698716)
- Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
- Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
- Type 2 diabetes ( 22885922 24509480 21874001 30297969 29632382 32499647 30718926 28869590)
- Type 2 diabetes (adjusted for BMI) ( 29632382)
- Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
- Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500)
- Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
- Waist circumference adjusted for BMI in active individuals ( 28448500)
- Waist circumference adjusted for BMI in non-smokers ( 28443625)
- Waist circumference adjusted for body mass index ( 34021172 25673412 28448500)
- Waist-hip index ( 34021172)
- Waist-hip ratio ( 25673412 20935629)
- Waist-to-hip ratio adjusted for BMI ( 34021172 26426971)
- Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
- Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971)
- Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
- Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500)
- Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
- Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500)
- Waist-to-hip ratio adjusted for BMI in inactive individuals ( 28448500)
- Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625)
- Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
- Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)
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Interacting Genes |
30 interacting genes:
AURKA
BRD4
CBLC
EEF1G
GABBR1
GRB10
GRB14
HDAC1
HDAC2
ITGAE
PML
RNF125
RNF7
SIRT1
SMARCA4
SMARCB1
SMARCD1
TRIM9
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E2
UBE2E3
UBE2I
UBE2L1
UBE2N
UBE2W
WDR47
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25 interacting genes:
CDC5L
CHFR
DAPK3
EGFR
ERBB2
FGFR1
FRS3
GIGYF1
GIGYF2
GOLGA2
HCK
IGF1R
INSR
IRS1
MAP3K14
MET
PDGFRA
PDGFRB
PRKCZ
SQSTM1
STK26
TEK
TNKS2
TRIM27
TRIM55
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Entrez ID |
55743 |
2888 |
HPRD ID |
05552 |
03313 |
Ensembl ID |
ENSG00000072609
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ENSG00000115290
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Uniprot IDs |
Q96EP1
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Q14449
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PDB IDs |
1LGP
1LGQ
2XOC
2XOY
2XOZ
2XP0
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2AUG
2AUH
4K81
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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