VPS35 and GNL1

Number of citations of the paper that reports this interaction (PubMedID 33305682)
2

Data Source:
BioGRID (unspecified method)

		VPS35	GNL1
Description		VPS35 retromer complex component	G protein nucleolar 1 (putative)
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Cytosol Endosome Membrane Retromer Complex Retromer, Cargo-selective Complex Extracellular Exosome Tubular Endosome Mitochondrion-derived Vesicle	Extracellular Space Nucleus
	Molecular Function	Protein Binding D1 Dopamine Receptor Binding	GTPase Activity Structural Molecule Activity GTP Binding
	Biological Process	Intracellular Protein Transport Positive Regulation Of Gene Expression Regulation Of Mitochondrion Organization Wnt Signaling Pathway Regulation Of Macroautophagy Regulation Of Protein Stability Regulation Of Cellular Protein Metabolic Process Endocytic Recycling Protein Localization To Endosome Retrograde Transport, Endosome To Golgi Mitochondrial Fragmentation Involved In Apoptotic Process Transcytosis Negative Regulation Of Inflammatory Response Positive Regulation Of Dopamine Receptor Signaling Pathway Negative Regulation Of Cell Death Positive Regulation Of Mitochondrial Fission Mitochondrion To Lysosome Transport Neurotransmitter Receptor Transport, Endosome To Plasma Membrane Negative Regulation Of Neuron Death Negative Regulation Of Late Endosome To Lysosome Transport Regulation Of Dendritic Spine Maintenance Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Presynapse Assembly Regulation Of Terminal Button Organization	T Cell Mediated Immunity Cellular Response To DNA Damage Stimulus Signal Transduction
Pathways		WNT ligand biogenesis and trafficking
Drugs
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Lung cancer ( 28604730) Major depressive disorder ( 27479909) Neuroticism ( 29255261) Rosacea symptom severity ( 29771307) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		15 interacting genes: APP DRD1 GNL1 LINC01554 MTNR1B PRPF19 SLC11A2 SNX1 SNX3 VEGFA VPS26A VPS26B VPS29 YBX1 ZNF512B	9 interacting genes: DAXX GDI1 KRT6A PRKN PTP4A1 SIRPA VPS35 YIF1A ZNF212
Entrez ID		55737	2794
HPRD ID		06085	00879
Ensembl ID		ENSG00000069329	ENSG00000204590
Uniprot IDs		Q96QK1	A0A024RCR2 B4DYK6 P36915
PDB IDs		2R17 5F0J 5F0K 5F0L 5F0M 5F0P 5OSH 5OSI 7BLN 7BLO
Enriched GO Terms of Interacting Partners?
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