FAM222B and PDLIM4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FAM222B	PDLIM4
Description		family with sequence similarity 222 member B	PDZ and LIM domain 4
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm	Stress Fiber Nucleus Cytoplasm Cytoskeleton Adherens Junction Z Disc Lamellipodium Early Endosome Membrane Early Endosome Lumen Filamentous Actin Recycling Endosome Lumen Dendritic Spine Postsynaptic Membrane Perinuclear Region Of Cytoplasm Recycling Endosome Membrane
	Molecular Function	Protein Binding	Actin Binding Protein Binding Protein Phosphatase Binding Protein Homodimerization Activity Metal Ion Binding Muscle Alpha-actinin Binding Alpha-actinin Binding
	Biological Process		Heart Development Actin Cytoskeleton Organization Actin Cytoskeleton Reorganization Muscle Structure Development Excitatory Chemical Synaptic Transmission
Pathways
Drugs
Diseases
GWAS		Estimated glomerular filtration rate reduction (30%) ( 30955190) Hemoglobin ( 32888494) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular hemoglobin concentration ( 32888494 27863252) Mean corpuscular volume ( 29403010 32888494 27863252) Red blood cell count ( 32888494) Red cell distribution width ( 27863252)	Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Blood protein levels ( 30072576) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908 22412388) Height ( 28552196) Inflammatory bowel disease ( 28067908 23128233) Mosquito bite size ( 28199695) Serum metabolite levels ( 23093944) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)
Interacting Genes		35 interacting genes: ANKRD10 BAG4 BANP BPIFA1 C10orf55 C19orf54 CDCA4 CNFN FAM168B FHL3 FOSB HYI INTS11 KRTAP11-1 KRTAP26-1 KRTAP3-1 LRRC61 OIP5 PDLIM4 PFDN5 PLA2G10 PRR20A PRR20B PRR20C PRR20D PRR20E RUNX1 SOHLH1 TRIP6 TSC1 TTLL12 UBQLN2 UFSP1 WWOX ZMYND12	8 interacting genes: ABCA1 AMT FAM222B PTPN13 RBPMS SDCBP TRIP6 ZNF408
Entrez ID		55731	8572
HPRD ID		07693	04571
Ensembl ID		ENSG00000173065	ENSG00000131435
Uniprot IDs		A0A024QZ60 B3KQ88 B3KTH5 B4DRX9 Q8WU58	A0A0S2Z4N4 P50479
PDB IDs			2EEG 2V1W 4Q2O
Enriched GO Terms of Interacting Partners?
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