RBM22 and AQR

Number of citations of the paper that reports this interaction (PubMedID 22365833)
163

Data Source:
BioGRID (two hybrid, two hybrid)

		RBM22	AQR
Description		RNA binding motif protein 22	aquarius intron-binding spliceosomal factor
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GO Annotations	Cellular Component	Prp19 Complex Nucleus Nucleoplasm Cytoplasm U2-type Catalytic Step 1 Spliceosome U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Membrane U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	RNA Binding Protein Binding U6 SnRNA Binding Pre-mRNA Binding Metal Ion Binding Calcium-dependent Protein Binding	RNA Binding Single-stranded RNA Binding MRNA Binding Protein Binding ATP Binding ATP Hydrolysis Activity 3'-5' RNA Helicase Activity
	Biological Process	MRNA Splicing, Via Spliceosome Positive Regulation Of RNA Splicing Positive Regulation Of Protein Import Into Nucleus MRNA Cis Splicing, Via Spliceosome Positive Regulation Of Protein Export From Nucleus Cellular Response To Xenobiotic Stimulus	MRNA Splicing, Via Spliceosome
Pathways		mRNA Splicing - Major Pathway	Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908)
Interacting Genes		16 interacting genes: AQR CEP55 CYSRT1 DRD2 GIGYF1 GOLGA2 HNRNPUL1 HOMER3 NCKIPSD OGT PRNP RBFOX2 RBM4 RNU6-1 RNU6-50P RNU6-6P	42 interacting genes: CHRNA7 MIR1-1 MIR106A MIR106B MIR107 MIR128-2 MIR145 MIR15B MIR199A2 MIR19B1 MIR19B2 MIR200B MIR200C MIR205 MIR206 MIR20B MIR214 MIR221 MIR222 MIR25 MIR29A MIR31 MIR34A MIR34B MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR92A2 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7D MIRLET7E MIRLET7G MIRLET7I PQBP1 RASGRP1 RBM22 RBM4 WDR77
Entrez ID		55696	9716
HPRD ID		10186	12468
Ensembl ID		ENSG00000086589	ENSG00000021776
Uniprot IDs		Q9NW64	A0A024R9L1 O60306
PDB IDs		2YTC 5MQF 5XJC 5YZG 5Z56 5Z57 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV 6ZYM 7A5P 7AAV 7ABG 7ABI	4PJ3 5MQF 5XJC 5YZG 5Z56 5Z57 6FF7 6ICZ 6ID0 6ID1 6QDV 7A5P 7ABI
Enriched GO Terms of Interacting Partners?
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