RUFY2 and BMX

Number of citations of the paper that reports this interaction (PubMedID 11877430)
27

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo, two hybrid)

		RUFY2	BMX
Description		RUN and FYVE domain containing 2	BMX non-receptor tyrosine kinase
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endosome	Nucleoplasm Cytosol Plasma Membrane Ruffle Membrane
	Molecular Function	SH3 Domain Binding Metal Ion Binding	Protein Tyrosine Kinase Activity Transmembrane Receptor Protein Tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Protein Binding ATP Binding Metal Ion Binding
	Biological Process	Biological_process Regulation Of Endocytosis	Adaptive Immune Response Protein Phosphorylation Phosphatidylinositol Biosynthetic Process Apoptotic Process Cell Adhesion Signal Transduction Mesoderm Development Intracellular Signal Transduction Peptidyl-tyrosine Autophosphorylation Protein Autophosphorylation B Cell Receptor Signaling Pathway
Pathways			Apoptotic cleavage of cellular proteins Synthesis of PIPs at the plasma membrane
Drugs			Fostamatinib Zanubrutinib
Diseases
GWAS		Hip circumference adjusted for BMI ( 34021172)
Interacting Genes		7 interacting genes: BMX DUSP23 EPHA3 RAB33A RAB33B SF3B3 TSPAN15	26 interacting genes: APP BCAR1 BIRC2 BTK CASP3 CAV1 CLNK EGFR ERBB2 FBXO25 ITK KDR NOPCHAP1 PAK1 PTK2 PTPN21 PTPRD RAP1A RUFY1 RUFY2 SRC STAT1 STAT3 STAT5A TEC TNFRSF1B
Entrez ID		55680	660
HPRD ID		11526	02111
Ensembl ID		ENSG00000204130	ENSG00000102010
Uniprot IDs		Q5GIA6 Q8WXA3	P51813
PDB IDs			2EKX 2YS2 3SXR 3SXS 6I99
Enriched GO Terms of Interacting Partners?
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