POMGNT1 and ZBTB18

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		POMGNT1	ZBTB18
Description		protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)	zinc finger and BTB domain containing 18
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Integral Component Of Membrane Integral Component Of Golgi Membrane	Heterochromatin Nucleus Nucleoplasm Nuclear Speck
	Molecular Function	Protein Binding Acetylglucosaminyltransferase Activity Manganese Ion Binding Beta-1,3-galactosyl-O-glycosyl-glycoprotein Beta-1,3-N-acetylglucosaminyltransferase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Protein O-linked Glycosylation O-glycan Processing	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Skeletal Muscle Tissue Development Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3 O-linked glycosylation
Drugs
Diseases
GWAS		Body mass index ( 26426971)	Adventurousness ( 30643258) General risk tolerance (MTAG) ( 30643258) Mercury levels ( 26025379)
Interacting Genes		12 interacting genes: BRCA1 CD74 CISD2 CXCL8 CXorf66 ERGIC3 LNX1 MBD1 RXYLT1 SOX6 TMEM237 ZBTB18	10 interacting genes: CTBP1 DNMT3A DNMT3B FCGR2B MYLIP PAK1 PIK3R3 POMGNT1 TSN ZBTB2
Entrez ID		55624	10472
HPRD ID		09493	12231
Ensembl ID		ENSG00000085998	ENSG00000179456
Uniprot IDs		B7Z7F2 B7Z7Q4 Q8WZA1	Q99592
PDB IDs		5GGF 5GGG 5GGI 5GGJ 5GGK 5GGL 5GGN 5GGO 5GGP 5XFC
Enriched GO Terms of Interacting Partners?
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