RPRD1A and BCAR3

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		RPRD1A	BCAR3
Description		regulation of nuclear pre-mRNA domain containing 1A	BCAR3 adaptor protein, NSP family member
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GO Annotations	Cellular Component	Nucleoplasm RNA Polymerase II, Holoenzyme	Cytoplasm Focal Adhesion Membrane
	Molecular Function	RNA Polymerase II Complex Binding Protein Binding	Phosphotyrosine Residue Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding Kinase Binding
	Biological Process	MRNA 3'-end Processing Dephosphorylation Of RNA Polymerase II C-terminal Domain	Lens Morphogenesis In Camera-type Eye Signal Transduction Small GTPase Mediated Signal Transduction Insulin Receptor Signaling Pathway Response To Xenobiotic Stimulus Positive Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of MAPK Cascade Positive Regulation Of GTPase Activity Positive Regulation Of DNA Replication Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Endothelin Receptor Signaling Pathway
Pathways		RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
Drugs
Diseases
GWAS		Drug-induced torsades de pointes ( 24223155) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494)	Alzheimer's disease progression score ( 29860282) Blood urea nitrogen levels ( 31152163) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Estimated glomerular filtration rate ( 31152163) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Liver fibrosis (total hepatic collagen content) ( 32953199) Major depressive disorder ( 27777418) Systolic blood pressure ( 30224653)
Interacting Genes		12 interacting genes: BCAR3 FAM90A1 HGS KDM1A KPNA3 LONRF1 NXF1 RIOK2 SDCBP YWHAZ ZNF410 ZNF76	38 interacting genes: AGR3 AP1M1 APP ATAD2 BAP1 BEX1 BEX2 CASZ1 CCDC57 CCL5 CST6 DKK3 EGFR EPSTI1 ERBB2 ERBB3 ERBB4 ERRFI1 GAB1 GAS8 GLCE GREB1 HOXC6 KIT KPNA1 MET MTA3 NEDD9 NSD3 OSGIN1 PDLIM2 PRDM14 PSMC3IP RPRD1A SERPINB5 THRSP UBASH3A VPS45
Entrez ID		55197	8412
HPRD ID		10134	05268
Ensembl ID		ENSG00000141425	ENSG00000137936
Uniprot IDs		A0A024RC37 A0A0C4DGQ6 Q96P16	A0A384MTS3 B3KNL6 B3KP06 O75815
PDB IDs		4JXT 4NAC	3T6A
Enriched GO Terms of Interacting Partners?
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