NADSYN1 and KRT5

		NADSYN1	KRT5
Description		NAD synthetase 1	keratin 5
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GO Annotations	Cellular Component	Cytoplasm Cytosol	Nucleus Cytoplasm Cytosol Intermediate Filament Membrane Keratin Filament Extracellular Exosome
	Molecular Function	NAD+ Synthase (glutamine-hydrolyzing) Activity Glutaminase Activity Protein Binding ATP Binding	Structural Constituent Of Cytoskeleton Protein Binding Scaffold Protein Binding
	Biological Process	NAD Biosynthetic Process 'de Novo' NAD Biosynthetic Process	Cytoskeleton Organization Epidermis Development
Pathways		Nicotinate metabolism	Type I hemidesmosome assembly Keratinization Formation of the cornified envelope
Drugs		Glutamic acid	Zinc Zinc acetate
Diseases
GWAS		Systemic lupus erythematosus ( 26502338) Vitamin D insufficiency ( 20541252) Vitamin D levels ( 29343764 20418485) Vitamin D levels (dietary vitamin D intake interaction) ( 29343764)	Basal cell carcinoma ( 31174203 33549134 24403052 25855136 27539887) Cutaneous squamous cell carcinoma ( 32041948) Keratinocyte cancer (MTAG) ( 31174203) Non-melanoma skin cancer ( 29739929) Squamous cell carcinoma ( 31174203)
Interacting Genes		15 interacting genes: ANKS1A COL8A1 CREB5 CUTC FRS3 GPANK1 HGS HOXC8 KRT5 MYO15B NOXA1 NTAQ1 PKD1 TFG UPF1	35 interacting genes: ALOX12 ALOX12B APC DCTN1 DSP DST EVPL GPD1 INCA1 KIFC3 KRT1 KRT14 KRT15 KRT16 KRT18 KRT19 KRT24 KRT25 KRT27 KRT28 KRT31 KRT35 KRT38 KRT4 KRT40 KRT6A KRT6B KRT7 NADSYN1 PKP2 SAP18 SORD TARBP2 TCHP UBE3A
Entrez ID		55191	3852
HPRD ID		16309	01010
Ensembl ID		ENSG00000172890	ENSG00000186081
Uniprot IDs		Q6IA69	P13647
PDB IDs		6OFB	3TNU 6JFV
Enriched GO Terms of Interacting Partners?
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