FIGN and CHERP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FIGN	CHERP
Description		fidgetin, microtubule severing factor	calcium homeostasis endoplasmic reticulum protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Microtubule Organizing Center Microtubule Nuclear Matrix	Nucleoplasm Cytoplasm Membrane Sarcoplasmic Reticulum Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding ATP Binding Protein C-terminus Binding Microtubule-severing ATPase Activity	RNA Binding Protein Binding Transmembrane Transporter Binding
	Biological Process	Cell Cycle Microtubule Severing Cell Division	RNA Processing Cellular Calcium Ion Homeostasis Nervous System Development Negative Regulation Of Cell Population Proliferation Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Calcineurin-NFAT Signaling Cascade
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Blood pressure ( 24954895 21572416 21909110) BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index ( 25673413) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body shape index ( 34021172) Chronic kidney disease ( 26831199) Coronary artery disease ( 32469254 33020668) Daytime nap ( 33568662) Diastolic blood pressure ( 28739976 27618452) Diastolic blood pressure (cigarette smoking interaction) ( 29455858) Diisocyanate-induced asthma ( 25918132) Folate pathway vitamin levels ( 19744961) General risk tolerance (MTAG) ( 30643258) Hip circumference adjusted for BMI ( 28552196) Hypertension ( 30487518) Immunoglobulin A vasculitis ( 28698626) Mean arterial pressure ( 26390057 29403010 30487518) Myocardial infarction ( 33532862) Platinum-induced myelosuppression in non-small cell lung cancer ( 25823687) Polycystic ovary syndrome (metabolic subtype) ( 32574161) PR interval ( 30046033 32439900) Pulse pressure ( 27841878 28739976 30487518) Response to antipsychotic treatment ( 19680635) Systolic blood pressure ( 26390057 28135244 27841878 29403010 28739976 27618447 27618452) Systolic blood pressure (cigarette smoking interaction) ( 29455858) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172)
Interacting Genes		2 interacting genes: CHERP HGS	49 interacting genes: ADAMTSL4 AGGF1 APBB1 ARGLU1 C1orf94 CCAR1 CLK3 EWSR1 FASTK FIGN FRA10AC1 HNRNPH3 KRTAP11-1 LASP1 LUC7L MAD1L1 MAGED1 MIR106B MIR200C MIR363 MIRLET7A2 MIRLET7C MIRLET7D MIRLET7E MIRLET7G MIRLET7I PPIL4 PRPF38A PRPF40A RACK1 RBFOX2 RBM23 RBM39 RBM7 RNPS1 SART1 SAXO1 SF3B4 SNRNP27 SNRNP70 SORBS3 SRPK1 SRPK2 TLE3 TTC14 U2AF1 U2AF2 USP54 WBP4
Entrez ID		55137	10523
HPRD ID		07287	13051
Ensembl ID		ENSG00000182263	ENSG00000085872
Uniprot IDs		Q5HY92	Q8IWX8
PDB IDs
Enriched GO Terms of Interacting Partners?
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