PPP1R2 and LMTK2

Number of citations of the paper that reports this interaction (PubMedID 12393858)
38

Data Source:
HPRD (in vivo, in vitro)

		PPP1R2	LMTK2
Description		protein phosphatase 1 regulatory inhibitor subunit 2	lemur tyrosine kinase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Early Endosome Golgi Apparatus Cytosol Integral Component Of Plasma Membrane Integral Component Of Membrane Growth Cone Neuronal Cell Body Receptor Complex Perinuclear Region Of Cytoplasm Recycling Endosome
	Molecular Function	Protein Phosphatase Inhibitor Activity Protein Serine/threonine Phosphatase Inhibitor Activity Protein Binding	Protein Serine/threonine Kinase Activity Transmembrane Receptor Protein Tyrosine Kinase Activity Protein Phosphatase Inhibitor Activity Protein Binding ATP Binding Myosin VI Binding Protein Serine Kinase Activity
	Biological Process	Glycogen Metabolic Process Generation Of Precursor Metabolites And Energy Regulation Of Signal Transduction Negative Regulation Of Catalytic Activity Regulation Of Phosphoprotein Phosphatase Activity	Receptor Recycling Protein Phosphorylation Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Multicellular Organism Development Axonogenesis Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Endocytic Recycling Transferrin Transport Positive Regulation Of Kinase Activity Negative Regulation Of Catalytic Activity Early Endosome To Late Endosome Transport Protein Autophosphorylation
Pathways
Drugs
Diseases
GWAS			Gamma glutamyl transferase levels ( 29403010 33339817) Hemoglobin levels ( 32327693) Prostate cancer ( 18264097) Type 2 diabetes or prostate cancer (pleiotropy) ( 33290408)
Interacting Genes		12 interacting genes: CDK5 CSNK2A1 CSNK2A2 GSK3B LMTK2 NEK2 PPP1CA PPP1CC PPP1R9A PPP1R9B TERF2IP TINF2	24 interacting genes: CDC14A CDC25C CDK5 CDK5R1 DUSP14 DUSP19 DUSP29 DUSP6 ILKAP MTMR6 PPM1A PPM1F PPM1K PPP1CA PPP1CB PPP1CC PPP1R2 PPP3CB PTPDC1 PTPN12 PTPN6 PTPRR STYX TPTE2
Entrez ID		5504	22853
HPRD ID		03478	13994
Ensembl ID		ENSG00000184203	ENSG00000164715
Uniprot IDs		P41236	Q8IWU2
PDB IDs
Enriched GO Terms of Interacting Partners?
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