PIH1D1 and LRCH3

Number of citations of the paper that reports this interaction (PubMedID 28514442)
406

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		PIH1D1	LRCH3
Description		PIH1 domain containing 1	leucine rich repeats and calponin homology domain containing 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Pre-snoRNP Complex R2TP Complex Ribonucleoprotein Complex	Cytoplasm Cytosol
	Molecular Function	RNA Polymerase I Core Promoter Sequence-specific DNA Binding RNA Polymerase I Cis-regulatory Region Sequence-specific DNA Binding Protein Binding Protein Kinase Binding Histone Binding ATPase Binding Phosphoprotein Binding	Protein Binding
	Biological Process	Box C/D SnoRNP Assembly RNA Polymerase I Preinitiation Complex Assembly Chromatin Remodeling RRNA Processing Epithelial Cell Differentiation Positive Regulation Of Protein-containing Complex Assembly SnoRNA Localization Regulation Of Histone H3-K4 Methylation Establishment Of Protein Localization To Chromatin Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K9 Dimethylation Negative Regulation Of Histone H3-K9 Trimethylation Positive Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I Positive Regulation Of Glucose Mediated Signaling Pathway Regulation Of TORC2 Signaling Positive Regulation Of TORC1 Signaling Positive Regulation Of Histone H3-K9 Acetylation Negative Regulation Of Histone H4-K16 Acetylation Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway	Septin Cytoskeleton Organization
Pathways
Drugs
Diseases
GWAS			Airway responsiveness in chronic obstructive pulmonary disease ( 25514360)
Interacting Genes		20 interacting genes: BYSL CA4 CDCA7L EAF1 FAM90A1 FARP1 GEM LRCH3 MAPK6 MFAP1 MISP PLEKHN1 RBPMS RCOR3 RPAP2 SCNM1 SEPTIN1 SMARCD1 TNS4 TSC22D4	5 interacting genes: DGCR6L DNAAF11 MYO6 PIH1D1 YWHAG
Entrez ID		55011	84859
HPRD ID		07938	14308
Ensembl ID		ENSG00000104872	ENSG00000186001
Uniprot IDs		Q9NWS0	B4DU23 Q96II8
PDB IDs		4PSF 4PSI 6GXZ 7AVC
Enriched GO Terms of Interacting Partners?
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