TESC and WBP11

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		TESC	WBP11
Description		tescalcin	WW domain binding protein 11
Image		No pdb structure
GO Annotations	Cellular Component	Ruffle Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Lamellipodium Ruffle Membrane	Nucleus Nucleoplasm Spliceosomal Complex Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Magnesium Ion Binding Protein Kinase Inhibitor Activity Calcium Ion Binding Protein Binding Phosphatase Inhibitor Activity Protein Homodimerization Activity	Single-stranded DNA Binding RNA Binding Protein Binding WW Domain Binding
	Biological Process	Negative Regulation Of Cell Population Proliferation Male Gonad Development Positive Regulation Of Gene Expression Protein Transport Megakaryocyte Differentiation Positive Regulation Of Granulocyte Differentiation Positive Regulation Of Sodium:proton Antiporter Activity Regulation Of Cell Adhesion Mediated By Integrin Negative Regulation Of Catalytic Activity Positive Regulation Of Megakaryocyte Differentiation Positive Regulation Of Transcription, DNA-templated Protein Stabilization Protein Maturation Cellular Response To Retinoic Acid Protein Localization To Plasma Membrane	RRNA Processing MRNA Cis Splicing, Via Spliceosome
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Dentate gyrus granule cell layer volume ( 30279459) Dentate gyrus molecular layer volume ( 30279459) Hippocampal subfield CA1 volume ( 30279459) Hippocampal subfield CA4 volume ( 30279459) Hippocampal tail volume ( 30279459) Mean platelet volume ( 32888494 27863252) Plateletcrit ( 32888494) PR interval ( 32439900) Total hippocampal volume ( 30279459)	Hip circumference adjusted for BMI ( 34021172)
Interacting Genes		7 interacting genes: CCDC91 DYNLT3 HMG20A RAI1 RPL36 SLC9A1 WBP11	33 interacting genes: APBB1 ARF1 C5orf22 CD2BP2 CTNNBL1 CYGB DDX17 DDX5 FYN GIGYF2 GRB2 ITSN1 MCRS1 MORN4 NCK2 NOD2 PIK3R1 PPP1CA PPP1CB PPP1CC PQBP1 PRPF40A RBM5 RTN4IP1 RUNX1T1 SEC23A SRC TESC TRAF4 TRIP10 UBASH3A VIM WBP4
Entrez ID		54997	51729
HPRD ID		11649	18293
Ensembl ID		ENSG00000088992	ENSG00000084463
Uniprot IDs		Q96BS2	A0A024RAW9 Q9Y2W2
PDB IDs			7ABF 7ABG
Enriched GO Terms of Interacting Partners?
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