PINX1 and UBL5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PINX1	UBL5
Description		PIN2 (TERF1) interacting telomerase inhibitor 1	ubiquitin like 5
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromosome Kinetochore Chromosome, Telomeric Region Nucleoplasm Nucleolus Mitochondrion Spindle	Nucleus Cytoplasm
	Molecular Function	Protein Binding Telomerase Inhibitor Activity Protein-containing Complex Binding Telomerase RNA Binding	Protein Binding Protein Tag
	Biological Process	Telomere Maintenance Via Telomerase Mitotic Metaphase Plate Congression Negative Regulation Of Cell Population Proliferation Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Protein Ubiquitination Regulation Of Protein Stability Negative Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomerase Activity Negative Regulation Of Telomerase Activity Protein Localization To Chromosome, Telomeric Region Protein Localization To Nucleolus Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Telomeric DNA Binding Positive Regulation Of Protein Localization To Nucleolus	MRNA Splicing, Via Spliceosome Cellular Protein Modification Process Positive Regulation Of Protein Targeting To Mitochondrion
Pathways
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Anxiety/tension (special factor of neuroticism) ( 30867560) Aspartate aminotransferase levels ( 33547301) Autism spectrum disorder ( 30804558) Body shape index ( 34021172) Brain morphology (MOSTest) ( 32665545) Carotid intima media thickness ( 30510157 21909108) Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Fish- and plant-related diet ( 32066663) General factor of neuroticism ( 30867560) General risk tolerance (MTAG) ( 30643258) Gut microbiota (beta diversity) ( 27723756) Lymphocyte counts ( 32888494 27863252) Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962) Medication use (calcium channel blockers) ( 31015401) Retinal vascular caliber ( 21060863) Serum alkaline phosphatase levels ( 33547301) Systemic lupus erythematosus ( 26316170) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Triglyceride levels ( 28334899 32154731) Triglycerides ( 24097068 30275531 20686565) Type 2 diabetes ( 30054458) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) White blood cell count ( 32888494 27863252)	Sleep duration ( 30531941) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
Interacting Genes		21 interacting genes: AIDA APP ARHGEF10 BNIP1 C14orf119 CACYBP DLGAP2 EIF1AD GABPA GYS1 MCRS1 MPZ PAFAH1B2 PTP4A3 RP1L1 TERF1 TERT TLK1 TNPO2 TP63 UBL5	48 interacting genes: BEND7 BIN3 C1QTNF1 CCDC196 CCDC28B CERCAM CLK1 CLK2 CLK4 CTAG1A CTAG1B FAM50B FANCI GCSAML HESX1 HID1 HMGXB4 HOXA1 HSPB2 KRTAP10-8 KRTAP13-3 LENG1 MBD3L1 NCOA5 NFYA NME4 NRIP3 PAX4 PHACTR3 PINX1 PRMT8 PSME2 SART1 SEPTIN2 SERTAD3 SF1 SMCP SPANXB1 SPATC1L TEX35 THAP3 TLE5 TRIM27 TRIM39 WASHC1 ZFP41 ZNF124 ZNF618
Entrez ID		54984	59286
HPRD ID		05934	06028
Ensembl ID		ENSG00000254093	ENSG00000198258
Uniprot IDs		Q96BK5	A0A024R7B0 Q9BZL1
PDB IDs			1P0R 4PYU 6AHD 7AAV 7ABF 7ABG 7ABI
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
Tagcloud (Intersection) ?