LIME1 and PNPO

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		LIME1	PNPO
Description		Lck interacting transmembrane adaptor 1	pyridoxamine 5'-phosphate oxidase
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Integral Component Of Membrane B Cell Receptor Complex	Cytosol
	Molecular Function	Protein Binding Protein Kinase Binding	Pyridoxamine-phosphate Oxidase Activity Protein Binding FMN Binding Pyridoxal Phosphate Binding Protein Homodimerization Activity
	Biological Process	Adaptive Immune Response Regulation Of Transcription By RNA Polymerase II Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of MAP Kinase Activity T Cell Receptor Signaling Pathway B Cell Receptor Signaling Pathway Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of NIK/NF-kappaB Signaling	Pyridoxine Biosynthetic Process Pyridoxal Phosphate Biosynthetic Process
Pathways			Vitamins B6 activation to pyridoxal phosphate
Drugs			Pyridoxal phosphate Flavin mononucleotide Mercaptoethanol
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Apolipoprotein A1 levels ( 33730874) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Bell's palsy ( 33602968) Crohn's disease ( 28067908) Estimated glomerular filtration rate ( 31015462) Inflammatory bowel disease ( 28067908 23128233) Meat-related diet ( 32066663) Prostate cancer ( 23535732) Refractive error ( 32231278) Ulcerative colitis ( 28067908)	Body mass index ( 26426971) Generalized epilepsy ( 30531953 22949513)
Interacting Genes		46 interacting genes: AGR3 AIG1 AQP1 ARFGAP3 BNIP2 C14orf180 CALN1 CIAO2A CLN6 EMD FRMD8 GAD2 GOSR2 GRB2 LCK LHFPL5 LPAR3 LYN MAN2B2 MEST MIEF2 NDRG4 NINJ1 PBX3 PKMYT1 PLCG2 PNPO PTPN9 RTP2 SEC22C SLC41A2 SNAP47 SNX1 STX6 STX7 TBRG4 TMBIM6 TMEM143 TMEM243 TMEM74 TMEM86B TMEM97 TRAF3IP3 UNC93B1 UPK2 ZFPL1	4 interacting genes: AGTRAP APP CMTM5 LIME1
Entrez ID		54923	55163
HPRD ID		07904	04476
Ensembl ID		ENSG00000203896	ENSG00000108439
Uniprot IDs		A0A087WT39 Q9H400	Q9NVS9 V9HW45
PDB IDs			1NRG 3HY8 6H00
Enriched GO Terms of Interacting Partners?
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