YTHDF1 and HSF4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		YTHDF1	HSF4
Description		YTH N6-methyladenosine RNA binding protein 1	heat shock transcription factor 4
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GO Annotations	Cellular Component	P-body Cytoplasm Cytoplasmic Stress Granule	Chromatin Nucleus Nuclear Speck
	Molecular Function	RNA Binding MRNA Binding Protein Binding Ribosome Binding N6-methyladenosine-containing RNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Identical Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Immune System Process Regulation Of Antigen Processing And Presentation Learning Memory Stress Granule Assembly Regulation Of MRNA Stability Positive Regulation Of Translation Positive Regulation Of Translational Initiation MRNA Destabilization Organelle Assembly Regulation Of Long-term Synaptic Potentiation Regulation Of Axon Guidance	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Visual Perception Positive Regulation Of Cell Population Proliferation Histone H3-K9 Demethylation Positive Regulation Of Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Cell Development Lens Fiber Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Response to cytadine analogues (cytosine arabinoside) ( 24483146)
Interacting Genes		19 interacting genes: ABHD11 BATF2 C6orf15 FAM168A HEY1 HSF4 ITSN2 KRTAP13-1 KRTAP26-1 KRTAP7-1 KRTAP8-1 LASP1 MAGED1 MSX2 OIP5 PRR32 TLE5 VPS37C ZNF34	46 interacting genes: AKAP8L ALKBH4 BBS2 C10orf55 C19orf54 CDK2AP2 CNOT1 DAXX DUSP26 FAM168B FOXH1 FOXI1 GFOD1 HGS INTS11 KRT31 KRT37 KRT38 KRT40 KRTAP19-6 KRTAP19-7 KRTAP3-1 KRTAP6-2 MAPK1 MAPK14 MAPK3 MAPK8 MKRN3 NHLRC4 NUDT21 NUP62 OIP5 PIH1D2 PITX1 PLA2G10 PPFIBP2 SESTD1 SLC27A5 SMARCA4 SOX10 STOML2 TPM3 UFSP1 YTHDF1 ZBED8 ZMYND12
Entrez ID		54915	3299
HPRD ID		11691	03896
Ensembl ID		ENSG00000149658	ENSG00000102878
Uniprot IDs		Q9BYJ9	A0A024R6X7 Q9ULV5
PDB IDs		4RCI 4RCJ	6J6V 6J6W
Enriched GO Terms of Interacting Partners?
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