CKMT1A and RXRG

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CKMT1A	RXRG
Description		creatine kinase, mitochondrial 1A	retinoid X receptor gamma
Image
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane	Chromatin Nucleoplasm Cytoplasm RNA Polymerase II Transcription Regulator Complex
	Molecular Function	Creatine Kinase Activity Protein Binding ATP Binding Kinase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Steroid Hormone Receptor Activity Nuclear Receptor Activity Protein Binding Zinc Ion Binding Retinoic Acid-responsive Element Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Phosphorylation Phosphocreatine Biosynthetic Process	Regulation Of Transcription By RNA Polymerase II Cell Differentiation Response To Retinoic Acid Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Retinoic Acid Receptor Signaling Pathway Anatomical Structure Development
Pathways		Creatine metabolism	Nuclear Receptor transcription pathway Signaling by Retinoic Acid
Drugs		Creatine Phosphocreatine	Adapalene Bexarotene Rosiglitazone Acitretin Alitretinoin Tretinoin Etretinate Bezafibrate Phthalic Acid Doconexent
Diseases
GWAS		Diastolic blood pressure ( 27841878)	AIDS ( 19754311) Bipolar disorder (age of onset <21) or attention deficit hyperactivity disorder ( 27890468) Bipolar disorder or attention deficit hyperactivity disorder ( 27890468) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Macular thickness ( 30535121) Menarche (age at onset) ( 27182965 21102462 29773799 25231870) Metabolite levels ( 23823483) Personality traits in bipolar disorder ( 21368711) Proportion of activated microglia (midfrontal cortex) ( 30679421) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		12 interacting genes: ASB9 CKM CTNNA3 HPCA KMT2A NUTF2 OCM OGT PPP1R16A PSMC3 RXRG VDAC1	33 interacting genes: CAMK2B CEBPZ CHGB CKMT1A CKMT1B CREBBP DCK FBXL4 HOXD4 ITGB3BP LRSAM1 MAP4 MPPED2 NCOA6 NCOR2 NR0B2 NR1H2 NR1H3 NR1H4 NR1I2 NR4A1 PICK1 PNO1 PPARA PPARD PPARG RARA RARB RARG SRF THRA THRB VDR
Entrez ID		548596	6258
HPRD ID		18683	01579
Ensembl ID		ENSG00000223572	ENSG00000143171
Uniprot IDs		P12532	A0A087WZ88 F1D8Q7 F1T097 P48443
PDB IDs		1QK1	2GL8 7A79
Enriched GO Terms of Interacting Partners?
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