FBXL12 and FXYD3

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		FBXL12	FXYD3
Description		F-box and leucine rich repeat protein 12	FXYD domain containing ion transport regulator 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol SCF Ubiquitin Ligase Complex	Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome
	Molecular Function	Protein Binding	Chloride Channel Activity Sodium Channel Regulator Activity
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Protein Ubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Entrainment Of Circadian Clock By Photoperiod Regulation Of Cell Cycle	Potassium Ion Transport Sodium Ion Transport Chloride Transport Regulation Of Sodium Ion Transmembrane Transporter Activity
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation	Ion homeostasis Ion transport by P-type ATPases Potential therapeutics for SARS
Drugs
Diseases
GWAS		Pursuit maintenance gain ( 29064472)
Interacting Genes		24 interacting genes: A2M ALDH3A1 APOE CDC37 CDKN1C DOCK8 ECSIT FBF1 FXYD3 GEMIN4 LNX1 MARCHF2 MAST1 PSEN1 PSEN2 PSME3 RNF32 SHFL SMAD1 TGFBR1 UBE2D3 ZNF44 ZNF562 ZNF823	64 interacting genes: AGR3 ANK1 AQP6 AQP9 BCL2L13 BEST2 CD79A CNR2 CREB3 CREB3L1 CYB5R3 EBP ERG28 ERGIC3 FAM209A FBXL12 FCGR2A FFAR2 GHITM GPR152 GPR37L1 GPR42 GPRC5D IBSP KASH5 KCNN4 LMNA LTC4S MAPK6 MFSD11 MFSD5 MGST1 MTIF3 NR4A1 NUDT3 PLPP6 SCN3B SERBP1 SGPL1 SLC10A1 SLC10A6 SLC16A12 SLC18A1 SLC1A1 SLC30A2 SLC35A1 SLC35B1 SLC35C2 SLC39A2 SPNS3 STRIT1 STX3 TIMM23 TIMMDC1 TLCD1 TMBIM6 TMEM179B TMEM50B TMEM52B TMEM80 TMEM86A TMEM97 TSPO2 XKR3
Entrez ID		54850	5349
HPRD ID		12363	05410
Ensembl ID		ENSG00000127452	ENSG00000089356
Uniprot IDs		Q9NXK8	Q14802
PDB IDs
Enriched GO Terms of Interacting Partners?
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