NDE1 and NOMO1

		NDE1	NOMO1
Description		nudE neurodevelopment protein 1	NODAL modulator 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Kinetochore Centrosome Cytosol Kinesin Complex Microtubule Membrane Spindle Pole Centrosome Cleavage Furrow Synapse	Cellular_component Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Microtubule Binding Protein Domain Specific Binding Identical Protein Binding	Protein Binding Carbohydrate Binding Ribosome Binding
	Biological Process	Establishment Of Mitotic Spindle Orientation Neuron Migration Microtubule Nucleation Chromosome Segregation Mitotic Centrosome Separation Neuroblast Proliferation Cell Migration Cerebral Cortex Development Vesicle Transport Along Microtubule Centrosome Duplication Cell Division Establishment Of Chromosome Localization Centrosome Localization	Biological_process Negative Regulation Of Nodal Signaling Pathway
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane RHO GTPases Activate Formins Mitotic Prometaphase AURKA Activation by TPX2 EML4 and NUDC in mitotic spindle formation
Drugs			Theophylline
Diseases
GWAS		Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Mean platelet volume ( 32888494) Multiple system atrophy (pathologically confirmed) ( 27629089) Serum immune biomarker levels ( 32066700) Serum uric acid levels in response to allopurinol in gout ( 25676789)
Interacting Genes		28 interacting genes: AR ARNT2 CDK1 DISC1 FAM9B FBXO7 GOLGA2 HOXA2 LZTS2 MAPK1 MED4 MKRN3 NDC80 NOMO1 PAFAH1B1 REL TFIP11 TRIM27 TSPOAP1 TTC1 TUBG1 UBQLN1 USHBP1 WAC YWHAG YWHAQ ZNF365 ZNF398	24 interacting genes: ATF7IP BAG6 BAIAP3 CASP4 CFB DLG4 ECT2 EXOSC10 KCNA1 MPV17L NCLN NDE1 NTAN1 PDZD3 PPIE SHBG STAT1 TOM1L1 TRIM55 TRIM63 UBQLN4 UPF2 VWF ZNF75A
Entrez ID		54820	23420
HPRD ID		14815	11398
Ensembl ID		ENSG00000072864	ENSG00000103512
Uniprot IDs		Q9NXR1 X5DP35 X5DR54	Q15155
PDB IDs
Enriched GO Terms of Interacting Partners?
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