BORCS6 and LAMTOR2

Number of citations of the paper that reports this interaction (PubMedID 28514442)
406

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		BORCS6	LAMTOR2
Description		BLOC-1 related complex subunit 6	late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
Image		No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane BORC Complex	Lysosomal Membrane Late Endosome Plasma Membrane Endosome Membrane Specific Granule Membrane Tertiary Granule Membrane Ragulator Complex
	Molecular Function	Protein Binding Identical Protein Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding Molecular Adaptor Activity
	Biological Process	Lysosome Localization	Regulation Of Cell Growth Fibroblast Migration Positive Regulation Of TOR Signaling Cellular Protein Localization Positive Regulation Of MAPK Cascade Regulation Of Catalytic Activity Cellular Response To Amino Acid Stimulus Regulation Of Cell-substrate Junction Organization Protein Localization To Cell Junction
Pathways			Macroautophagy MTOR signalling mTORC1-mediated signalling Energy dependent regulation of mTOR by LKB1-AMPK TP53 Regulates Metabolic Genes MAP2K and MAPK activation Neutrophil degranulation Regulation of PTEN gene transcription Amino acids regulate mTORC1
Drugs
Diseases
GWAS
Interacting Genes		35 interacting genes: ABI2 BEX2 C19orf25 C1orf109 C1orf216 DISC1 EPS8 EXOC8 EXOSC5 FAM161B FAM9C FBXO44 FCHSD2 GAS8 HAUS1 HGS INSYN1 KANK2 KXD1 LAMTOR2 LNX1 MED21 MOS NDEL1 NTAQ1 OSTF1 PKNOX1 PLA2G4A RCOR3 RIBC1 SHPRH SPG21 TACC2 USHBP1 ZNF655	3 interacting genes: BORCS6 ERBB3 LAMTOR3
Entrez ID		54785	28956
HPRD ID		13368	17463
Ensembl ID		ENSG00000196544	ENSG00000116586
Uniprot IDs		Q96GS4	Q9Y2Q5
PDB IDs			5X6U 5X6V 5Y39 5Y3A 6B9X 6EHP 6EHR 6NZD 6U62 6ULG 6WJ2 6WJ3
Enriched GO Terms of Interacting Partners?
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