ALKBH4 and MLLT3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ALKBH4	MLLT3
Description		alkB homolog 4, lysine demethylase	MLLT3 super elongation complex subunit
Image		No pdb structure
GO Annotations	Cellular Component	Nucleolus Cytoplasm Midbody Contractile Ring	Nucleus Nucleoplasm Chromosome Cytosol Transcription Elongation Factor Complex Extracellular Exosome
	Molecular Function	Actin Binding Protein Binding Oxidoreductase Activity 2-oxoglutarate-dependent Dioxygenase Activity Demethylase Activity Oxidative DNA Demethylase Activity Metal Ion Binding	DNA Binding Chromatin Binding Protein Binding Histone Binding Lysine-acetylated Histone Binding Modification-dependent Protein Binding
	Biological Process	Chromatin Organization Protein Demethylation Actomyosin Structure Organization Oxidative DNA Demethylation Cleavage Furrow Ingression Oxidative Demethylation DNA Demethylation Regulation Of Chromatin Organization	Segment Specification Anterior/posterior Pattern Specification Gene Expression Positive Regulation Of Transcription, DNA-templated Hematopoietic Stem Cell Differentiation Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Chromatin Organization Regulation Of Stem Cell Division Positive Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway
Pathways			Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Morning person ( 30696823)	Atrial fibrillation ( 29892015) Dietary fat liking ( 32516399) Estimated glomerular filtration rate ( 31152163) Hematocrit ( 32888494) Hemoglobin ( 32888494) Mean reticulocyte volume ( 32888494) Platelet distribution width ( 32888494) Response to montelukast in asthma (change in FEV1) ( 26083242) Systolic blood pressure ( 30578418)
Interacting Genes		20 interacting genes: BPIFA1 DTX2 EIF3C EP300 FAM168A GORASP2 HSF4 KMT2E LCN2 MEPCE MLLT1 MLLT3 MTMR6 NIF3L1 PSMA6 TCF4 TES TRAF4 TXNL4B ZFHX3	20 interacting genes: AFF1 ALKBH4 APP APPBP2 BCOR CBX8 CDK6 COL6A1 EEF1A1 FAM9A H3C1 LRIF1 LRRK2 MCM6 MIIP PTN RBM48 SGK1 VAX1 ZNF572
Entrez ID		54784	4300
HPRD ID		07875	01163
Ensembl ID		ENSG00000160993	ENSG00000171843
Uniprot IDs		Q9NXW9	A0A0S2Z448 P42568
PDB IDs			2LM0 2MV7 2N4Q 2NDF 2NDG 4TMP 5HJB 5HJD 5YYF 6B7G 6L5Z 6LS6 6MIL 6MIM
Enriched GO Terms of Interacting Partners?
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