HYDIN and PEF1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		HYDIN	PEF1
Description		HYDIN axonemal central pair apparatus protein	penta-EF-hand domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Axonemal Central Apparatus Axonemal Central Pair Projection	Cytoplasm Endoplasmic Reticulum COPII Vesicle Coat Cul3-RING Ubiquitin Ligase Complex Extracellular Exosome
	Molecular Function		RNA Binding Calcium Ion Binding Protein Binding Identical Protein Binding Protein Heterodimerization Activity Protein Dimerization Activity Calcium-dependent Protein Binding Ubiquitin Ligase-substrate Adaptor Activity
	Biological Process	Epithelial Cell Development Cilium Movement Ventricular System Development Trachea Development Axonemal Central Apparatus Assembly	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Neural Crest Formation Neural Crest Cell Development Protein Ubiquitination COPII Vesicle Coating Response To Calcium Ion Positive Regulation Of Protein Monoubiquitination
Pathways
Drugs			Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Celiac disease ( 23936387) Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Coffee consumption ( 31046077) Diastolic blood pressure ( 30578418) Hematocrit ( 27863252) LDL cholesterol levels ( 32203549) Low density lipoprotein cholesterol levels ( 32154731) Malaria ( 31844061) Pulse pressure ( 30578418)	Asthma ( 31959851) Body mass index ( 26426971) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) General cognitive ability ( 29844566) Hypoalbuminemia ( 34050200) Intelligence (MTAG) ( 29326435) Severe aortic features in Marfan syndrome ( 30087447)
Interacting Genes		5 interacting genes: CFDP1 CIAO2B ERRFI1 PEF1 UBC	40 interacting genes: AKAP8L ALG2 ANKRD10 BAG4 BPIFA1 C11orf1 CALCOCO2 CEP55 CTAG1A CTAG1B CUL3 DAZAP2 DMRTB1 EIF4G1 EWSR1 FAM168A FOXR2 HEMK1 HGS HYDIN INCA1 KLHL12 KRTAP12-1 KRTAP15-1 KRTAP19-1 MED25 METTL15 NR0B2 PDCD6 SEC24A SEC31A SMUG1 SOHLH1 SPAG8 SPG21 STH TFG VPS37C WWOX ZIC1
Entrez ID		54768	553115
HPRD ID		11042	10143
Ensembl ID		ENSG00000157423	ENSG00000162517
Uniprot IDs		Q4G0P3	A0A384MQX5 Q9UBV8
PDB IDs		2E6J 2YS4
Enriched GO Terms of Interacting Partners?
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