POU4F1 and MAPRE3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		POU4F1	MAPRE3
Description		POU class 4 homeobox 1	microtubule associated protein RP/EB family member 3
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Neuron Projection RNA Polymerase II Transcription Regulator Complex	Cytoplasm Microtubule Organizing Center Midbody Microtubule Plus-end Spindle Midzone Mitotic Spindle Astral Microtubule End
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding Single-stranded DNA Binding Protein Binding Sequence-specific DNA Binding GTPase Binding Sequence-specific Double-stranded DNA Binding	Protein Binding Microtubule Binding Protein C-terminus Binding Protein Kinase Binding Identical Protein Binding Microtubule Plus-end Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Suckling Behavior Ventricular Compact Myocardium Morphogenesis Regulation Of Transcription By RNA Polymerase II Axonogenesis Synapse Assembly Mesoderm Development Heart Development Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Cell Migration In Hindbrain Trigeminal Nerve Development Central Nervous System Neuron Differentiation Habenula Development Neuron Projection Development Positive Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of Osteoclast Differentiation Positive Regulation Of Transcription By RNA Polymerase II Neuron Fate Specification Sensory System Development Peripheral Nervous System Neuron Development Regulation Of Neurogenesis Regulation Of DNA-binding Transcription Factor Activity Proprioception Involved In Equilibrioception Regulation Of Cell Cycle Innervation Cellular Response To Cytokine Stimulus Cellular Response To Estradiol Stimulus Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Positive Regulation Of Transcription Regulatory Region DNA Binding Negative Regulation Of Transcription Elongation By RNA Polymerase I	Protein Localization Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Microtubule Polymerization Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Protein Kinase Activity Positive Regulation Of Transcription, DNA-templated Spindle Assembly Cell Division Positive Regulation Of Microtubule Plus-end Binding Protein Localization To Microtubule Plus-end
Pathways		Regulation of TP53 Activity through Association with Co-factors
Drugs
Diseases
GWAS		Antipsychotic drug-induced weight gain in schizophrenia ( 31447353) Total ventricular volume (Alzheimer's disease interaction) ( 21116278)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Estimated glomerular filtration rate in non-diabetics ( 31451708) Leftâ€“right brain asymmetry ( 33723403) Lymphocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Post bronchodilator FEV1/FVC ratio ( 26634245) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		5 interacting genes: ESR1 EWSR1 MAPRE3 NDFIP2 RIT2	57 interacting genes: ANKRD1 APC2 AURKA AURKB C20orf202 C4orf45 CCSER1 CHRDL2 CLASP1 CRTAC1 DCTN2 DDIT4L DOK4 EIF4E2 FAM161B FOXD4L1 FOXD4L4 FXR2 GAS2L2 GTF2F2 GTSE1 HROB IKZF1 JUN KIF19 KLHDC7B KNSTRN LAP3 LHX4 LMO2 MAPRE2 MARCHF7 MEOX2 MRPL12 PDE4DIP PICK1 POU4F1 PSMA1 PSMB1 PSRC1 RAB1A REL SDCBP SIAH1 SLAIN1 SPDYE2 SPDYE2B TEX43 TLE5 TRAIP TRIM14 TXN2 YAF2 ZC2HC1A ZC2HC1C ZNF526 ZNF547
Entrez ID		5457	22924
HPRD ID		03379	16156
Ensembl ID		ENSG00000152192	ENSG00000084764
Uniprot IDs		Q01851	Q9UPY8
PDB IDs			1WYO 3CO1 3JAK 3JAL 3JAR 3TQ7
Enriched GO Terms of Interacting Partners?
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