DDX4 and SPSB4

Number of citations of the paper that reports this interaction (PubMedID 20561531)
26

Data Source:
BioGRID (unspecified method)

		DDX4	SPSB4
Description		DEAD-box helicase 4	splA/ryanodine receptor domain and SOCS box containing 4
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm P Granule Perinuclear Region Of Cytoplasm Pi-body PiP-body	Cytosol SCF Ubiquitin Ligase Complex
	Molecular Function	RNA Binding RNA Helicase Activity ATP Binding ATP Hydrolysis Activity	Protein Binding Ubiquitin Ligase-substrate Adaptor Activity
	Biological Process	Male Meiotic Nuclear Division Male Meiosis I Gamete Generation Spermatogenesis Negative Regulation Of Transposition Cell Differentiation Flagellated Sperm Motility Gene Silencing By RNA PiRNA Metabolic Process DNA Methylation Involved In Gamete Generation PiRNA Biosynthetic Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Intracellular Signal Transduction Regulation Of Circadian Rhythm Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Rhythmic Process Positive Regulation Of Protein Polyubiquitination
Pathways		PIWI-interacting RNA (piRNA) biogenesis RND3 GTPase cycle	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Cocaine dependence ( 31212010)	Ischemic stroke ( 24262325) Response to citalopram or escitalopram in depression ( 27622933) Schizophrenia x sex interaction ( 34099189) Stroke (ischemic) ( 23041239)
Interacting Genes		5 interacting genes: PIWIL2 RANBP9 SPSB1 SPSB2 SPSB4	3 interacting genes: DDX4 NOS2 PAWR
Entrez ID		54514	92369
HPRD ID		05593	18108
Ensembl ID		ENSG00000152670	ENSG00000175093
Uniprot IDs		Q9NQI0	Q96A44
PDB IDs			2V24 6DN7 6DN8
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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