XRN1 and PABPC4

  • Number of citations of the paper that reports this interaction (PubMedID 15231747)
  • 57
  • Data Source:
  • HPRD (two hybrid)

XRN1

PABPC4

Description 5'-3' exoribonuclease 1 poly(A) binding protein cytoplasmic 4
Image No pdb structure No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Benign childhood epilepsy with centro-temporal spikes ( 32580138)
  • Birth weight ( 31043758)
  • Caffeine consumption from coffee or tea ( 33287642)
  • Heel bone mineral density ( 30598549)
  • Mean spheric corpuscular volume ( 32888494)
  • Mosquito bite size ( 28199695)
  • Parkinson's disease motor subtype (tremor to postural instability/gait difficulty score ratio) ( 33987465)
  • Waist-hip ratio ( 28552196)
  • Apolipoprotein A1 levels ( 32203549)
  • Brain morphology (min-P) ( 32665545)
  • Brain morphology (MOSTest) ( 32665545)
  • C-reactive protein levels ( 30388399 21300955)
  • C-reactive protein levels or HDL-cholesterol levels (pleiotropy) ( 27286809)
  • C-reactive protein levels or triglyceride levels (pleiotropy) ( 27286809)
  • Chronic obstructive pulmonary disease ( 30804561)
  • Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143)
  • Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143)
  • Coffee consumption ( 31046077)
  • Cortical surface area (min-P) ( 32665545)
  • Cortical surface area (MOSTest) ( 32665545)
  • Cortical thickness (min-P) ( 32665545)
  • Cortical thickness (MOSTest) ( 32665545)
  • Diastolic blood pressure ( 27618448)
  • HDL cholesterol ( 24097068 30275531 25961943 20686565)
  • HDL cholesterol levels ( 32203549 28334899 30698716)
  • HDL cholesterol levels in current drinkers ( 30698716)
  • HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535)
  • High density lipoprotein cholesterol levels ( 29615537)
  • Mean arterial pressure ( 27618448)
  • Mean corpuscular hemoglobin ( 32888494)
  • Mean corpuscular hemoglobin concentration ( 32888494)
  • Mean corpuscular volume ( 32888494)
  • Medication use (drugs used in diabetes) ( 31015401)
  • Metabolic syndrome ( 31589552)
  • Red cell distribution width ( 32888494 27863252)
  • Subcortical volume (min-P) ( 32665545)
  • Subcortical volume (MOSTest) ( 32665545)
  • Triglyceride levels ( 32203549)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Walking pace ( 33128006)
Interacting Genes 67 interacting genes: ADGRE5 ALDOA ANGPTL6 AP1G2 ATP5MC2 B3GALT6 BAG6 C1GALT1 CBX5 CCT5 CENPBD1P CHD4 CTSB CTSH DCP1B DNASE2 DPP7 DXO EXOSC1 EXOSC10 EXOSC6 EXOSC8 FADS1 FBXO7 GLMP HEATR1 HERC2P4 HNRNPA1 KATNB1 LDHA LEPR LGALS3BP LINC01541 LSM4 MAN2C1 MFSD5 MIR34C MIR429 MIR7-1 MTCH2 MTREX MYH10 NDUFA13 NDUFB10 NDUFB9 PABPC4 PLEKHG2 POLD2 PPP2CA PRADC1 PSMB5 RBMX RNF187 SDHB SKIV2L SMARCD2 SNHG1 SPATA20 SRRM2 STAM2 TMEM50A UPF1 UPF2 UPF3B VWA5B2 WAPL ZFP36 26 interacting genes: CDC42 DUX4 EEF1A1 FOXD3 GDF9 HAP1 HCRTR1 IL7R LUC7L2 MED31 MKNK1 MTF1 NMNAT1 OGT PHLDA1 PRKCG RIF1 S100A8 SETDB1 SMAD9 SREK1 SRPK2 UBC VPS26B XRN1 ZNF655
Entrez ID 54464 8761
HPRD ID 10470 04557
Ensembl ID ENSG00000114127 ENSG00000090621
Uniprot IDs Q8IZH2 Q13310
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?