HAO1 and PEX5

Number of citations of the paper that reports this interaction (PubMedID 20178365)
21

Data Source:
BioGRID (unspecified method)

		HAO1	PEX5
Description		hydroxyacid oxidase 1	peroxisomal biogenesis factor 5
Image
GO Annotations	Cellular Component	Peroxisome Peroxisomal Matrix Cytosol	Cytoplasm Peroxisome Peroxisomal Membrane Golgi Apparatus Cytosol Membrane Protein-containing Complex
	Molecular Function	(S)-2-hydroxy-acid Oxidase Activity FMN Binding	Peroxisome Targeting Sequence Binding Peroxisome Matrix Targeting Signal-1 Binding Protein Binding Enzyme Binding Small GTPase Binding Peroxisome Membrane Targeting Sequence Binding Protein N-terminus Binding Protein Sequestering Activity
	Biological Process	Fatty Acid Alpha-oxidation Response To Oxidative Stress Glycolate Catabolic Process	Protein Import Into Peroxisome Matrix Protein Import Into Peroxisome Matrix, Docking Negative Regulation Of Protein-containing Complex Assembly Protein Import Into Peroxisome Membrane
Pathways		Glyoxylate metabolism and glycine degradation Peroxisomal protein import Peroxisomal protein import	Pexophagy
Drugs		N-sulfo-flavin mononucleotide Benzoylformic Acid 3-Decyl-2,5-Dioxo-4-Hydroxy-3-Pyrroline Flavin mononucleotide Phenylpyruvic acid 4-Carboxy-5-(1-Pentyl)Hexylsulfanyl-1,2,3-Triazole 5-(dodecylthio)-1H-1,2,3-triazole-4-carboxylic acid 3-(INDOL-3-YL) LACTATE (2S)-2-HYDROXYOCTANOIC ACID Lumasiran
Diseases
GWAS		Childhood ear infection ( 27182965) Colorectal cancer ( 30529582 24836286 23263487) Colorectal cancer or advanced adenoma ( 30510241) Dentures ( 31235808) Heel bone mineral density ( 30598549) Hip minimal joint space width ( 27701424) Nose morphology ( 29921221) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Ossification of the posterior longitudinal ligament of the spine ( 25064007) QT interval ( 29213071) Smoking status (heavy vs light) ( 28520984) Systemic lupus erythematosus ( 26502338)	IgG glycosylation ( 23382691) Night sleep phenotypes ( 27126917) Refractive error ( 32231278)
Interacting Genes		1 interacting genes: PEX5	77 interacting genes: ACD ACOT2 ACOT4 ACOT8 ACOX2 ACOX3 AGXT AMACR ANKRD50 ATM BAAT BRCA1 CAPRIN2 CCDC14 CROT DAO DDO DECR2 DHRS4 ECI2 EP400P1 EPHX2 GDPD5 GLMN GNPAT GSTK1 HACL1 HAO1 HAO2 HMGCL HNRNPH1 HOXA7 HSPA1A IDE IDH1 LDHB LONP2 MKRN3 MLYCD MPV17 NOS2 NUDT19 NUDT3 NUDT7 NUFIP2 PAOX PDZK1 PEX1 PEX10 PEX12 PEX13 PEX14 PEX26 PEX6 PEX7 PIPOX POT1 PRDX5 PRR13 PSAP RPL14 S100A6 SCARB1 SCP2 SCRN2 SIRT3 SLC27A2 SNUPN SSTR5 TIMMDC1 TINF2 TM6SF1 TOMM7 USP2 USP9X ZFAND3 ZNF772
Entrez ID		54363	5830
HPRD ID		05429	02684
Ensembl ID		ENSG00000101323	ENSG00000139197
Uniprot IDs		A8K058 Q9UJM8	A0A0S2Z480 A0A0S2Z4F3 A0A0S2Z4H1 B4DR50 B4E0T2 P50542
PDB IDs		2NZL 2RDT 2RDU 2RDW 2W0U 5QIB 5QIC 5QID 5QIE 5QIF 5QIG 5QIH 6GMB 6GMC	1FCH 2C0L 2C0M 2J9Q 2W84 3R9A 4BXU 4KXK 4KYO
Enriched GO Terms of Interacting Partners?
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