POLR2B and BTF3

Number of citations of the paper that reports this interaction (PubMedID 2320128)
43

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		POLR2B	BTF3
Description		RNA polymerase II subunit B	basic transcription factor 3
Image
GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleus Nucleoplasm RNA Polymerase II, Core Complex Membrane	Nucleus Cytosol Nascent Polypeptide-associated Complex Polysomal Ribosome
	Molecular Function	RNA Polymerase II Activity DNA Binding Chromatin Binding RNA Binding DNA-directed 5'-3' RNA Polymerase Activity Protein Binding Ribonucleoside Binding Metal Ion Binding	RNA Binding Protein Binding
	Biological Process	Transcription By RNA Polymerase II	In Utero Embryonic Development Transcription By RNA Polymerase II Protein Transport
Pathways		Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex RNA Pol II CTD phosphorylation and interaction with CE during HIV infection HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome Formation of HIV-1 elongation complex containing HIV-1 Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Abortive elongation of HIV-1 transcript in the absence of Tat Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation Viral Messenger RNA Synthesis MicroRNA (miRNA) biogenesis Transcriptional regulation by small RNAs PIWI-interacting RNA (piRNA) biogenesis Activation of anterior HOX genes in hindbrain development during early embryogenesis RNA Polymerase II Pre-transcription Events Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER TP53 Regulates Transcription of DNA Repair Genes FGFR2 alternative splicing RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes mRNA Capping mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Elongation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Pol II CTD phosphorylation and interaction with CE Signaling by FGFR2 IIIa TM Estrogen-dependent gene expression Inhibition of DNA recombination at telomere
Drugs
Diseases
GWAS		Age-related macular degeneration ( 21909106) Bitter alcoholic beverage consumption ( 31046077) Congenital heart disease (maternal effect) ( 28468790) Coronary artery disease ( 29212778) Height ( 20881960 25429064) Metabolite levels ( 23823483) White blood cell count ( 29403010)	Eyebrow thickness ( 26926045) Monobrow thickness ( 26926045)
Interacting Genes		19 interacting genes: BTF3 CALM1 CCNH CDK7 CTDP1 IKBKG ITCH LZTR1 MEN1 NEDD4 OTUD5 POLR2C POLR2D POLR2H POLR2L PTEN SNAR-B2 SUB1 ZSCAN1	14 interacting genes: APP CDC42 CSNK2B IFTAP MED21 NAA40 NMT2 NOTO POLR2B PTGIS TXLNA TXLNB USP16 ZDHHC17
Entrez ID		5431	689
HPRD ID		15943	03966
Ensembl ID		ENSG00000047315	ENSG00000145741
Uniprot IDs		B4DH29 B4DHJ3 C9J2Y9 P30876	P20290
PDB IDs		5IY6 5IY7 5IY8 5IY9 5IYA 5IYB 5IYC 5IYD 6DRD 6O9L	3LKX 3MCB
Enriched GO Terms of Interacting Partners?
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