FAM3B and BIN2

		FAM3B	BIN2
Description		FAM3 metabolism regulating signaling molecule B	bridging integrator 2
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Extracellular Exosome	Phagocytic Cup Podosome Extracellular Region Plasma Membrane Cell Cortex Cell Junction Secretory Granule Lumen Cell Projection Ficolin-1-rich Granule Lumen
	Molecular Function	Cytokine Activity Protein Binding	Protein Binding Phospholipid Binding
	Biological Process	Apoptotic Process Signal Transduction Insulin Secretion Glucose Homeostasis	Phagocytosis, Engulfment Cell Chemotaxis Podosome Assembly Plasma Membrane Tubulation
Pathways			Neutrophil degranulation Signaling by membrane-tethered fusions of PDGFRA or PDGFRB
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Elevated serum carcinoembryonic antigen levels ( 24941225) Glycemic traits (pregnancy) ( 23903356) Tumor biomarkers ( 23300138)	Aging (time to death) ( 21782286) Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Mean platelet volume ( 32888494 27863252) Platelet count ( 32888494)
Interacting Genes		8 interacting genes: APP BIN2 COL6A1 FCGR2A FUT3 H2BS1 KCNAB2 MAP3K7CL	5 interacting genes: APPBP2 FAM3B POT1 TERF1 TINF2
Entrez ID		54097	51411
HPRD ID		10552	05805
Ensembl ID		ENSG00000183844	ENSG00000110934
Uniprot IDs		P58499	Q9UBW5
PDB IDs			4AVM 4I1Q
Enriched GO Terms of Interacting Partners?
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