PLXNA2 and IFT80

Number of citations of the paper that reports this interaction (PubMedID 12421765)
41

Data Source:
HPRD (two hybrid)

		PLXNA2	IFT80
Description		plexin A2	intraflagellar transport 80
Image			No pdb structure
GO Annotations	Cellular Component	Semaphorin Receptor Complex Plasma Membrane Integral Component Of Plasma Membrane	Cytoplasm Centrosome Cilium Intraciliary Transport Particle B Ciliary Basal Body Ciliary Tip 9+0 Non-motile Cilium
	Molecular Function	Protein Binding Semaphorin Receptor Activity Identical Protein Binding
	Biological Process	Somitogenesis Negative Regulation Of Cell Adhesion Regulation Of Cell Shape Neural Tube Development Cerebellar Granule Cell Precursor Tangential Migration Regulation Of Cell Migration Regulation Of GTPase Activity Positive Regulation Of Axonogenesis Centrosome Localization Pharyngeal System Development Limb Bud Formation Semaphorin-plexin Signaling Pathway Semaphorin-plexin Signaling Pathway Involved In Axon Guidance	Osteoblast Differentiation Endochondral Ossification Growth Plate Cartilage Chondrocyte Differentiation Smoothened Signaling Pathway Osteoblast Proliferation Bone Mineralization Involved In Bone Maturation Negative Regulation Of Epithelial Cell Proliferation Limb Development Cilium Assembly Articular Cartilage Development Receptor Localization To Non-motile Cilium Non-motile Cilium Assembly Negative Regulation Of Non-canonical Wnt Signaling Pathway
Pathways		Sema3A PAK dependent Axon repulsion SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion CRMPs in Sema3A signaling CRMPs in Sema3A signaling Other semaphorin interactions	Intraflagellar transport Intraflagellar transport
Drugs
Diseases
GWAS		Adolescent idiopathic scoliosis ( 31417091) Bitter alcoholic beverage consumption ( 31046077) Cardiac hypertrophy ( 21348951) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) General risk tolerance (MTAG) ( 30643258) Lung cancer in never smokers ( 28604730) Manganese levels ( 26025379) Pursuit maintenance gain ( 29064472) Refractive error ( 32231278) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking status (ever vs never smokers) ( 30643258) Squamous cell lung carcinoma ( 28604730)	Alanine aminotransferase levels ( 34315874) Aspartate aminotransferase levels ( 34315874) Bipolar disorder ( 31043756) LDL cholesterol ( 30275531) Liver enzyme levels (alanine transaminase) ( 33972514) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Malaria ( 31844061)
Interacting Genes		6 interacting genes: CEMIP DHX37 FNBP4 HACE1 IFT80 UBAP2L	7 interacting genes: FGFR4 NMD3 OTOL1 PLXNA2 SLITRK3 UBXN10 ZBBX
Entrez ID		5362	57560
HPRD ID		03033	13853
Ensembl ID		ENSG00000076356	ENSG00000068885
Uniprot IDs		O75051	Q9P2H3
PDB IDs		3Q3J
Enriched GO Terms of Interacting Partners?
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