PLK1 and REST

  • Number of citations of the paper that reports this interaction (PubMedID 25453754)
  • 11
  • Data Source:
  • BioGRID (affinity chromatography technology, enzymatic study)

PLK1

REST

Description polo like kinase 1 RE1 silencing transcription factor
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adventurousness ( 30643258)
  • Age-related macular degeneration ( 21909106)
  • Coronary artery disease ( 32469254 26343387 33020668)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • General risk tolerance (MTAG) ( 30643258)
  • Heel bone mineral density ( 30598549)
  • Height ( 25429064 31562340)
  • Mean platelet volume ( 27863252)
  • Mean reticulocyte volume ( 32888494)
  • Migraine ( 27322543)
  • Myocardial infarction ( 33532862)
  • Plasma anti-thyroglobulin and anti-thyroid peroxidase levels (bivariate analysis) ( 29678681)
  • Platelet count ( 29403010)
  • Plateletcrit ( 32888494)
  • Response to bleomycin (chromatid breaks) ( 21106707)
  • Risk-taking tendency (4-domain principal component model) ( 30643258)
  • Smoking initiation (ever regular vs never regular) ( 30679032)
  • White blood cell count ( 32888494)
Interacting Genes 119 interacting genes: - ACTL6B APP ASPM BAG6 BCL2L1 BIRC6 BRCA2 BUB1 BUB1B C6orf136 CCDC115 CCNB1 CDC14A CDC25C CENPQ CEP55 CHEK2 CSN1S1 CSN2 CTNNB1 DNAJB9 DNHD1 ECT2 EIF6 FBXL5 FBXW7 GET4 GLB1 GORASP1 IKBKB INTS11 ITSN1 KIF23 KIF2C KLF4 KLHL22 KRBA1 LMO4 LRP5L LRRK1 LRRK2 MAD2L1BP MAGED1 MCM2 MCM3 MCM7 MDM2 MPP2 MYC MYT1 NEDD4 NHSL2 NINL NPM1 NUDC PARP10 PHC2 PIN1 PITPNM1 PKMYT1 PLK3 PPID PRC1 PRKN PSMA1 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PTEN PTPRD RABAC1 RACGAP1 RAD51 RAP1GAP RECQL5 RELA REST RGCC RICTOR RNF126 RNF2 RXRA SIMC1 SNCA SNCB SPOUT1 SREBF1 STAG2 STK3 STUB1 SUGT1 TANK TNFSF11 TOP2A TP53 TP53BP2 TP73 TPT1 TRIOBP TSC1 TUBA4A TUBB TUBB3 TUBG1 USP16 USP7 VRK3 WEE1 ZNF71 11 interacting genes: AURKA CDYL CEP135 GTF2B HTT MAPK1 PLK1 RCOR1 SIN3B SUB1 TBP
Entrez ID 5347 5978
HPRD ID 03652 08990
Ensembl ID ENSG00000166851 ENSG00000084093
Uniprot IDs P53350 A0A1W2PQA1 Q13127
PDB IDs 1Q4K 1Q4O 1UMW 2OGQ 2OJX 2OU7 2OWB 2RKU 2V5Q 2YAC 3BZI 3C5L 3FC2 3FVH 3HIH 3HIK 3KB7 3P2W 3P2Z 3P34 3P35 3P36 3P37 3Q1I 3RQ7 3THB 4A4L 4A4O 4DFW 4E67 4E9C 4E9D 4H5X 4H71 4HAB 4HCO 4HY2 4J52 4J53 4LKL 4LKM 4O56 4O6W 4O9W 4RCP 4WHH 4WHK 4WHL 4X9R 4X9V 4X9W 5J19 5NEI 5NFU 5NJE 5NMM 5NN1 5NN2 5TA6 5TA8 6AX4 6GY2 2CZY 6DU2 6DU3
Enriched GO Terms of Interacting Partners?
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