PLCB4 and MKKS

		PLCB4	MKKS
Description		phospholipase C beta 4	MKKS centrosomal shuttling protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Smooth Endoplasmic Reticulum Cytosol Postsynaptic Density Dendrite Parallel Fiber To Purkinje Cell Synapse Glutamatergic Synapse	Nucleus Cytoplasm Centrosome Cytosol Motile Cilium Kinociliary Basal Body
	Molecular Function	Phosphatidylinositol Phospholipase C Activity Phospholipase C Activity Calcium Ion Binding Protein Binding	Protein Binding ATP Binding Unfolded Protein Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Lipid Catabolic Process Phosphatidylinositol-mediated Signaling Modulation Of Chemical Synaptic Transmission	Heart Looping Protein Folding Spermatid Development Determination Of Left/right Symmetry Heart Development Visual Perception Sensory Perception Of Smell Gonad Development Negative Regulation Of Gene Expression Artery Smooth Muscle Contraction Striatum Development Hippocampus Development Cerebral Cortex Development Negative Regulation Of Actin Filament Polymerization Melanosome Transport Developmental Process Negative Regulation Of GTPase Activity Social Behavior Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway Positive Regulation Of Multicellular Organism Growth Vasodilation Fat Cell Differentiation Photoreceptor Cell Maintenance Negative Regulation Of Blood Pressure Intracellular Transport Brain Morphogenesis Detection Of Mechanical Stimulus Involved In Sensory Perception Of Sound Chaperone-mediated Protein Complex Assembly Cartilage Development Regulation Of Stress Fiber Assembly Pigment Granule Aggregation In Cell Center Convergent Extension Involved In Gastrulation Cilium Assembly Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Face Development Non-motile Cilium Assembly
Pathways		PLC beta mediated events PLC beta mediated events Synthesis of IP3 and IP4 in the cytosol G alpha (q) signalling events G alpha (q) signalling events	BBSome-mediated cargo-targeting to cilium
Drugs
Diseases
GWAS		Daytime sleep phenotypes ( 27126917) Evening vs. morning chronotype (self-assessed) ( 32579418) Initial pursuit acceleration ( 29064472) Initial pursuit acceleration in psychotic disorders ( 29064472) Metabolite levels ( 23823483) Neutrophil count ( 20172861)
Interacting Genes		4 interacting genes: MEOX2 MKKS NLGN3 REL	10 interacting genes: APP CDR2 IL2RB LAMP5 PLCB4 PRSS2 PTN SELENOP TMX4 ZBED1
Entrez ID		5332	8195
HPRD ID		02885	05356
Ensembl ID		ENSG00000101333	ENSG00000125863
Uniprot IDs		Q15147	B7Z3W9 Q9NPJ1
PDB IDs
Enriched GO Terms of Interacting Partners?
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