PKP2 and ITPR2

PKP2

ITPR2

Description plakophilin 2 inositol 1,4,5-trisphosphate receptor type 2
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alanine aminotransferase levels ( 33547301)
  • Amyotrophic lateral sclerosis ( 17827064)
  • Birth weight ( 31043758 27680694)
  • Body shape index ( 34021172)
  • BRCA1/2-negative high-risk breast cancer ( 30323354)
  • HDL cholesterol levels in HIV infection ( 33109212)
  • Heel bone mineral density ( 30598549)
  • Hip circumference adjusted for BMI ( 34021172)
  • Hip index ( 34021172)
  • Kashin-Beck disease ( 25303641)
  • LDL cholesterol levels ( 32203549)
  • Lipid traits (pleiotropy) (HIPO component 1) ( 30289880)
  • Liver enzyme levels (alanine transaminase) ( 33972514)
  • Lymphocyte counts ( 32888494)
  • Major depressive disorder ( 27479909)
  • Male-pattern baldness ( 27182965)
  • Offspring birth weight ( 31043758)
  • Plateletcrit ( 32888494)
  • Refractive error ( 32231278)
  • Renal cell carcinoma ( 31231134 22010048)
  • Retinitis pigmentosa ( 33514863)
  • Serum alkaline phosphatase levels ( 33547301)
  • Smooth-surface caries ( 24556642)
  • Type 2 diabetes ( 30054458 30297969)
  • Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
  • Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500)
  • Waist circumference adjusted for BMI in active individuals ( 28448500)
  • Waist circumference adjusted for body mass index ( 34021172 28448500)
  • Waist-hip index ( 34021172)
  • Waist-hip ratio ( 25673412 20935629)
  • Waist-to-hip ratio adjusted for BMI ( 34021172 26426971)
  • Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500)
  • Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500)
  • Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
  • Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)
Interacting Genes 45 interacting genes: ACTN3 AKAP9 ARMC8 CARD9 CASK CCDC120 CCDC125 CCHCR1 CTNNB1 DDX11 DMRTB1 DSC1 DSC2 DSG1 DSG2 DSP FHL3 GOLGA2 GRIPAP1 GTF2IRD1 HOOK2 HSPB2 ITPR2 JUP KDM5A KLC4 KRT18 KRT31 KRT5 MAGOHB MARK3 MTUS2 NCKIPSD NDEL1 PIBF1 PLEKHG4 POLR3A RABEP1 RBM5 ROPN1 SINHCAF SMAD9 SPTA1 TEKT4 YWHAG 6 interacting genes: BANK1 LINC01554 PKP2 PRKACA TRPC1 TRPC4
Entrez ID 5318 3709
HPRD ID 04177 02536
Ensembl ID ENSG00000057294 ENSG00000123104
Uniprot IDs Q99959 Q14571
PDB IDs 3TT9
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?