PIGR and RAB3B

Number of citations of the paper that reports this interaction (PubMedID 11832247)
29

Data Source:
HPRD (in vivo, in vitro)

		PIGR	RAB3B
Description		polymeric immunoglobulin receptor	RAB3B, member RAS oncogene family
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GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Azurophil Granule Membrane Receptor Complex Extracellular Exosome Secretory IgA Immunoglobulin Complex	Cytoplasm Endosome Golgi Apparatus Cytosol Plasma Membrane Synaptic Vesicle Vesicle Perinuclear Region Of Cytoplasm Extracellular Exosome Dopaminergic Synapse Anchored Component Of Synaptic Vesicle Membrane
	Molecular Function	Polymeric Immunoglobulin Receptor Activity Transmembrane Signaling Receptor Activity	GTPase Activity Protein Binding GTP Binding GDP Binding Myosin V Binding
	Biological Process	Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste Retina Homeostasis Immunoglobulin Transcytosis In Epithelial Cells Mediated By Polymeric Immunoglobulin Receptor Epidermal Growth Factor Receptor Signaling Pathway Fc Receptor Signaling Pathway Receptor Clustering	Vesicle Docking Involved In Exocytosis Protein Secretion Regulation Of Exocytosis Antigen Processing And Presentation Positive Regulation Of Dopamine Uptake Involved In Synaptic Transmission Protein Localization To Plasma Membrane Regulation Of Vesicle Size Regulation Of Synaptic Vesicle Cycle
Pathways		Neutrophil degranulation	RAB geranylgeranylation
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Coronary atherosclerosis (increased number of diseased vessels) (traffic exposure interaction) ( 28355232) Inflammatory bowel disease ( 23128233) Metabolite levels ( 23823483) Precuneus cortex volume ( 31530798)	Mean platelet volume ( 32888494)
Interacting Genes		4 interacting genes: AP1M1 CCL5 CD79A RAB3B	16 interacting genes: ACVR1 CALM1 CALM2 CALM3 CHM GDI1 PIGR RABIF RIMS2 RPH3A RPH3AL SGSM2 SMAD1 SMAD4 TGFBR1 VRTN
Entrez ID		5284	5865
HPRD ID		01436	01540
Ensembl ID		ENSG00000162896	ENSG00000169213
Uniprot IDs		P01833	P20337
PDB IDs		1XED 2OCW 3CHN 3CM9 5D4K 6KXS 6LX3 6LXW 6UE7 6UE8 6UE9 6UEA 7K0C	3DZ8
Enriched GO Terms of Interacting Partners?
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