ATP6V0C and NIPAL3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ATP6V0C	NIPAL3
Description		ATPase H+ transporting V0 subunit c	NIPA like domain containing 3
Image			No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Plasma Membrane Focal Adhesion Endosome Membrane Integral Component Of Membrane Phagocytic Vesicle Membrane Proton-transporting V-type ATPase, V0 Domain Azurophil Granule Membrane Extracellular Exosome Tertiary Granule Membrane Ficolin-1-rich Granule Membrane	Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism Proton-transporting ATPase Activity, Rotational Mechanism	Protein Binding Magnesium Ion Transmembrane Transporter Activity
	Biological Process	ATP Synthesis Coupled Proton Transport Regulation Of Macroautophagy Positive Regulation Of Wnt Signaling Pathway Proton Transmembrane Transport	Magnesium Ion Transport Magnesium Ion Transmembrane Transport
Pathways		ROS and RNS production in phagocytes Neutrophil degranulation Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport	Miscellaneous transport and binding events
Drugs		Tiludronic acid
Diseases
GWAS			Cutaneous malignant melanoma ( 32341527) Cutaneous melanoma or hair colour ( 32341527) Male-pattern baldness ( 28196072)
Interacting Genes		53 interacting genes: AQP6 ARF6 ASGR2 CD53 CD69 CD79A CERS2 CLEC14A CLEC17A CLEC2D CLIC1 CPLX4 CREB3 DNAJC1 DRD2 EDA EDA2R ERBB2 ERH EVI2A FAM210B FFAR2 GPR152 GPR25 GPR42 HSD17B13 HTR2C KLRC1 LMNA LRRC25 MARK3 MCEMP1 MDFI MSR1 NIPAL3 OPRM1 PDCD1LG2 PI16 PSMA3 RETREG3 SCN3B SLC35E3 SLC7A1 SMIM3 SPACA1 SSMEM1 STOM SUSD3 TMEM139 TMEM31 TMEM9 VSIR ZCCHC12	10 interacting genes: ATP6V0C CD79A EDA GJA5 GPX8 LMNA MANBAL MFF TMEM14B VMA21
Entrez ID		527	57185
HPRD ID		00162	13149
Ensembl ID		ENSG00000185883	ENSG00000001461
Uniprot IDs		P27449	A6NN97 Q6P499
PDB IDs		6WLW 6WM2 6WM3 6WM4
Enriched GO Terms of Interacting Partners?
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