TUBA8 and TCP1

Number of citations of the paper that reports this interaction (PubMedID 9885248)
14

Data Source:
HPRD (in vivo)

		TUBA8	TCP1
Description		tubulin alpha 8	t-complex 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Microtubule Microtubule Cytoskeleton	Pericentriolar Material Heterochromatin Acrosomal Vesicle Zona Pellucida Receptor Complex Golgi Apparatus Centrosome Cytosol Chaperonin-containing T-complex Microtubule Cell Body Extracellular Exosome
	Molecular Function	GTPase Activity Structural Constituent Of Cytoskeleton Protein Binding GTP Binding	RNA Binding Protein Binding ATP Binding Ubiquitin Protein Ligase Binding Protein Folding Chaperone Unfolded Protein Binding
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Cell Cycle	Protein Folding Tubulin Complex Assembly Binding Of Sperm To Zona Pellucida Positive Regulation Of Telomere Maintenance Via Telomerase Translocation Of Peptides Or Proteins Into Host Cell Cytoplasm Protein Stabilization Positive Regulation Of Telomerase Activity ScaRNA Localization To Cajal Body Toxin Transport Positive Regulation Of Establishment Of Protein Localization To Telomere Positive Regulation Of Protein Localization To Cajal Body Positive Regulation Of Telomerase RNA Localization To Cajal Body Regulation Of Macrophage Apoptotic Process
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane Gap junction assembly MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand Recruitment of NuMA to mitotic centrosomes Formation of tubulin folding intermediates by CCT/TriC Post-chaperonin tubulin folding pathway Recycling pathway of L1 Recycling pathway of L1 Cilium Assembly RHO GTPases activate IQGAPs RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase The role of GTSE1 in G2/M progression after G2 checkpoint Carboxyterminal post-translational modifications of tubulin Carboxyterminal post-translational modifications of tubulin HCMV Early Events Assembly and cell surface presentation of NMDA receptors Activation of AMPK downstream of NMDARs Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation Sealing of the nuclear envelope (NE) by ESCRT-III Kinesins	Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Folding of actin by CCT/TriC Association of TriC/CCT with target proteins during biosynthesis Association of TriC/CCT with target proteins during biosynthesis BBSome-mediated cargo-targeting to cilium Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs		Epothilone D Patupilone
Diseases
GWAS		Atrial fibrillation ( 30061737 29892015) Cerebrospinal T-tau levels ( 28247064)
Interacting Genes		9 interacting genes: CCT8L2 GRM7 LINC01554 MYC POTEH PXN SIAH1 TCP1 TCP11L2	16 interacting genes: CBFA2T2 CCT5 CCT7 CDC20 DUX4 FANCA OGT PDCL PTEN SH3BP4 SLC26A4-AS1 SUMO2 TUBA4A TUBA8 VRK2 YWHAQ
Entrez ID		51807	6950
HPRD ID		05763	01748
Ensembl ID		ENSG00000183785	ENSG00000120438
Uniprot IDs		Q9NY65	E7EQR6 P17987
PDB IDs			6NR8 6NR9 6NRA 6NRB 6NRC 6NRD 6QB8 7LUM 7LUP
Enriched GO Terms of Interacting Partners?
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