GNG13 and HAUS3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GNG13	HAUS3
Description		G protein subunit gamma 13	HAUS augmin like complex subunit 3
Image		No pdb structure
GO Annotations	Cellular Component	Heterotrimeric G-protein Complex Plasma Membrane Dendrite	Nucleoplasm Mitochondrion Centrosome Cytosol Microtubule Cytoskeleton Intercellular Bridge HAUS Complex Mitotic Spindle Mitotic Spindle Microtubule
	Molecular Function	Protein Binding G-protein Beta-subunit Binding	Molecular_function Protein Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Sensory Perception Of Taste	Centrosome Cycle Spindle Assembly Cell Division
Pathways		Activation of G protein gated Potassium channels Glucagon signaling in metabolic regulation G-protein activation Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Olfactory Signaling Pathway Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) ADP signalling through P2Y purinoceptor 12 G beta:gamma signalling through PI3Kgamma Prostacyclin signalling through prostacyclin receptor Prostacyclin signalling through prostacyclin receptor Adrenaline,noradrenaline inhibits insulin secretion Adrenaline,noradrenaline inhibits insulin secretion Ca2+ pathway Ca2+ pathway G alpha (q) signalling events G alpha (12/13) signalling events G beta:gamma signalling through PLC beta G alpha (s) signalling events ADP signalling through P2Y purinoceptor 1 ADP signalling through P2Y purinoceptor 1 G alpha (i) signalling events G alpha (z) signalling events Glucagon-type ligand receptors Thromboxane signalling through TP receptor Vasopressin regulates renal water homeostasis via Aquaporins Thrombin signalling through proteinase activated receptors (PARs) Thrombin signalling through proteinase activated receptors (PARs) Presynaptic function of Kainate receptors Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding G beta:gamma signalling through BTK G beta:gamma signalling through CDC42 Extra-nuclear estrogen signaling ADORA2B mediated anti-inflammatory cytokines production Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 32888494) Mean reticulocyte volume ( 32888494) Metabolite levels ( 23823483)
Interacting Genes		40 interacting genes: ABI3 ADAMTSL4 ADD3 BEX5 CCHCR1 CTAG1A CTAG1B CYSRT1 DISC1 DLG1 DLG4 EMILIN1 FTO GLRX3 GNAT3 GNB1 GNB2 GNB3 GNB4 GNB5 HAUS3 HOXA10 KRT27 KRT34 KRT37 KRT38 KRTAP9-2 LIN7B MEOX2 PAX5 PLSCR2 RASSF10 RPRM RSPO4 TEAD2 TEPSIN TRIM54 UQCC2 VPS16 WASHC3	8 interacting genes: ANKRD11 BRME1 CIAO1 GNG13 KDM1A RCOR3 TXLNA TXLNB
Entrez ID		51764	79441
HPRD ID		12116	10784
Ensembl ID		ENSG00000127588	ENSG00000214367
Uniprot IDs		Q9P2W3	Q68CZ6
PDB IDs			6PTB 6PTE
Enriched GO Terms of Interacting Partners?
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