PDZK1 and SLC15A2

Number of citations of the paper that reports this interaction (PubMedID 15553237)
13

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		PDZK1	SLC15A2
Description		PDZ domain containing 1	solute carrier family 15 member 2
Image
GO Annotations	Cellular Component	Plasma Membrane Brush Border Apical Plasma Membrane Brush Border Membrane Microvillus Membrane Membrane Raft Extracellular Exosome	Plasma Membrane Integral Component Of Plasma Membrane Apical Plasma Membrane Spanning Component Of Plasma Membrane Extracellular Exosome Spanning Component Of Membrane
	Molecular Function	Scavenger Receptor Binding Protein Binding PDZ Domain Binding Protein-membrane Adaptor Activity Protein-containing Complex Binding	Protein Binding Peptide:proton Symporter Activity Dipeptide Transmembrane Transporter Activity
	Biological Process	Carnitine Transport Positive Regulation Of Ion Transmembrane Transporter Activity Regulation Of Anion Transport Protein Localization To Plasma Membrane Positive Regulation Of Protein Targeting To Membrane Positive Regulation Of Cation Transmembrane Transport Positive Regulation Of Protein Localization To Membrane Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane	Ion Transport Protein Transport Peptidoglycan Transport Xenobiotic Transport Dipeptide Transport Innate Immune Response Renal Absorption Regulation Of Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Dipeptide Import Across Plasma Membrane Transport Across Blood-brain Barrier Proton Transmembrane Transport Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane
Pathways			Proton/oligopeptide cotransporters
Drugs			Ampicillin Cefotaxime Oxacillin Benzylpenicillin
Diseases
GWAS		Contrast sensitivity ( 24152035) Gout ( 33832965 32238385) Serum uric acid levels ( 30993211) Urate levels ( 31985003 20884846 31578528 23263486) Urate levels in overweight individuals ( 25811787) Uric acid levels ( 19503597)	Allergic disease (asthma, hay fever or eczema) ( 29083406) Estimated glomerular filtration rate ( 31152163 31015462 31451708 30604766) Glomerular filtration rate ( 29403010) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Multiple sclerosis ( 21833088) Multiple sclerosis and HDL levels (pleiotropy) ( 26920376) Platelet count ( 32888494) Plateletcrit ( 32888494)
Interacting Genes		31 interacting genes: ABCA1 ABCC2 ABCC4 ACE2 AKAP10 APP CFTR CLCN3 CRHR1 FARP2 GFAP PDZK1IP1 PEX5 RPS6KA1 SCARB1 SLC13A1 SLC15A2 SLC17A1 SLC22A11 SLC22A12 SLC22A4 SLC22A5 SLC26A6 SLC34A1 SLC9A3 SLC9A3R1 SLC9A3R2 SLCO1A2 SLK SSTR5 UBE2I	26 interacting genes: ADAM12 ANKS1A AQP1 C11orf87 CHRD ENKD1 KLHL38 KPRP KRT34 KRTAP12-2 KRTAP12-3 KRTAP15-1 KRTAP26-1 KRTAP6-3 LMO4 NTAQ1 OTX1 PDZD3 PDZK1 PITX1 PLSCR4 SMARCC1 TENT5B TLX3 VENTX WWOX
Entrez ID		5174	6565
HPRD ID		04829	09088
Ensembl ID		ENSG00000174827	ENSG00000163406
Uniprot IDs		Q5T2W1	Q16348
PDB IDs		2EEI 2EEJ 2VSP 3TMH 4Q2P 6EZI	6EZI
Enriched GO Terms of Interacting Partners?
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