DNAJB11 and UBR1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		DNAJB11	UBR1
Description		DnaJ heat shock protein family (Hsp40) member B11	ubiquitin protein ligase E3 component n-recognin 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Membrane Chaperone Complex	Ubiquitin Ligase Complex Proteasome Complex Cytoplasm Cytosol
	Molecular Function	Protein Binding Unfolded Protein Binding Misfolded Protein Binding	Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity Leucine Binding
	Biological Process	Protein Folding Positive Regulation Of ATPase Activity Protein Maturation	Protein Ubiquitination Negative Regulation Of TOR Signaling Cellular Response To Leucine Ubiquitin-dependent Protein Catabolic Process Via The N-end Rule Pathway
Pathways		XBP1(S) activates chaperone genes	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) MGMT methylation in smokers ( 26183928) Triglycerides ( 25961943)
Interacting Genes		26 interacting genes: ANKZF1 AP2M1 APOBEC1 BAG6 CEP70 COL6A1 CRMP1 DDAH2 DNAJC13 DRAP1 EIF3D EZH2 FAF1 GRB2 HSPA1A HTN3 PAXIP1 PTN SIMC1 SNX5 SPRED1 SUMO4 UBQLN4 UBR1 XPO1 ZZZ3	31 interacting genes: ANXA3 ARL15 ARL3 ARL4D ATF3 BCL2L1 BTBD2 CDC42 CDC6 DLEU1 DNAJB11 FOS FTH1 GADD45A GSK3B LAMA4 LAMTOR3 NDUFA4L2 NR3C1 NTAN1 NTAQ1 NUDT3 PKNOX1 PTPRS SERPINB9 SPRY2 TAC3 TP53I3 UBE2A UBE2B UBE2D2
Entrez ID		51726	197131
HPRD ID		07485	09342
Ensembl ID		ENSG00000090520	ENSG00000159459
Uniprot IDs		Q9UBS4	Q8IWV7
PDB IDs			3NY1 5TDC
Enriched GO Terms of Interacting Partners?
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