GPRC5B and FUCA2

Number of citations of the paper that reports this interaction (PubMedID 28298427)
23

Data Source:
BioGRID (two hybrid)

		GPRC5B	FUCA2
Description		G protein-coupled receptor class C group 5 member B	alpha-L-fucosidase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleoplasm Nucleolus Cytosol Plasma Membrane Cell Surface Integral Component Of Membrane Cytoplasmic Vesicle Membrane Intracellular Membrane-bounded Organelle Receptor Complex Extracellular Exosome	Extracellular Region Extracellular Space Lysosome Endoplasmic Reticulum Lumen Azurophil Granule Lumen Extracellular Exosome
	Molecular Function	G Protein-coupled Receptor Binding G Protein-coupled Receptor Activity Protein Kinase Binding Protein Kinase Activator Activity	Alpha-L-fucosidase Activity Protein Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Activation Of Protein Kinase Activity Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Neuron Differentiation Positive Regulation Of Inflammatory Response Positive Regulation Of Macrophage Cytokine Production Positive Regulation Of Protein Tyrosine Kinase Activity Positive Regulation Of Canonical Wnt Signaling Pathway	Fucose Metabolic Process Response To Bacterium Glycoside Catabolic Process Regulation Of Entry Of Bacterium Into Host Cell
Pathways			Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Neutrophil degranulation Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Anthropometric traits ( 30166351) Anthropometric traits (multi-trait analysis) ( 30166351) Birth weight ( 31043758) Body mass index ( 26961502 25673413 20935630 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Body size at age 10 ( 32376654) Childhood body mass index ( 33045005) Hip circumference ( 25673412) L-selectin levels ( 25576479) Menarche (age at onset) ( 25231870) Obesity ( 23563607) Obesity-related traits ( 23251661) Waist circumference ( 25673412)	Multiple sclerosis ( 31604244)
Interacting Genes		6 interacting genes: ADRB2 C11orf71 FUCA2 HSP90AB1 HTR2C TMEM120A	19 interacting genes: GPR37 GPRC5B GUCD1 HOXA1 KRTAP10-1 KRTAP4-12 KRTAP5-2 KRTAP5-3 LCE1A LCE1B LCE1E LCE4A MEOX2 NUFIP2 OGT PIN1 TNPO2 VWC2 WNT11
Entrez ID		51704	2519
HPRD ID		16177	00649
Ensembl ID		ENSG00000167191	ENSG00000001036
Uniprot IDs		A0A024QYX2 B7Z831 Q9NZH0	Q9BTY2
PDB IDs
Enriched GO Terms of Interacting Partners?
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