PALS2 and ARHGAP18

Number of citations of the paper that reports this interaction (PubMedID 15231747)
57

Data Source:
HPRD (two hybrid)

		PALS2	ARHGAP18
Description		protein associated with LIN7 2, MAGUK p55 family member	Rho GTPase activating protein 18
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Extracellular Exosome	Ruffle Cytoplasm Cytosol Cytoplasmic Microtubule Plasma Membrane Nuclear Speck
	Molecular Function	Protein Binding	GTPase Activator Activity Cadherin Binding
	Biological Process	Protein-containing Complex Assembly	Small GTPase Mediated Signal Transduction Regulation Of Cell Shape Regulation Of Actin Filament Polymerization Regulation Of Actin Cytoskeleton Organization Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Cell Motility
Pathways			RHOA GTPase cycle RHOC GTPase cycle
Drugs
Diseases
GWAS			Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel) ( 23648065) Antineutrophil cytoplasmic antibody-associated vasculitis ( 22808956) Axial length ( 24144296) Cognitive function ( 24684796) Heel bone mineral density ( 30598549) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917) Periodontal disease-related phenotype (Socransky) ( 24347629)
Interacting Genes		37 interacting genes: AATF ABCA1 ADGRA1 ARF5 ARHGAP18 DIS3 DNM2 DYNLRB1 EIF3G EXOSC10 EXOSC2 EXOSC4 EXOSC5 EXOSC6 EXOSC7 EXOSC8 EXOSC9 FTL KHDRBS1 KNSTRN LIN7A LIN7B LIN7C MKRN2 MT2P1 MTREX NDN NFKB1 OGT OSBPL3 PARN PTF1A RPS20 SMARCA4 SNX9 TACR3 THOP1	3 interacting genes: BCS1L MPHOSPH6 PALS2
Entrez ID		51678	93663
HPRD ID		09509	12474
Ensembl ID		ENSG00000105926	ENSG00000146376
Uniprot IDs		A0A024RA25 B8ZZG1 Q9NZW5	Q8N392
PDB IDs
Enriched GO Terms of Interacting Partners?
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