PPIL1 and N4BP2L2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PPIL1	N4BP2L2
Description		peptidylprolyl isomerase like 1	NEDD4 binding protein 2 like 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome	Nucleus Transcription Repressor Complex Extracellular Exosome
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Cyclosporin A Binding Disordered Domain Specific Binding	Molecular_function Transcription Corepressor Activity Protein Binding Enzyme Binding
	Biological Process	MRNA Splicing, Via Spliceosome Protein Peptidyl-prolyl Isomerization Protein Folding	Negative Regulation Of Transcription By RNA Polymerase II Blastocyst Development Positive Regulation Of Hematopoietic Stem Cell Proliferation Negative Regulation Of Hematopoietic Stem Cell Differentiation
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Blood protein levels ( 30072576 29875488) Heart rate ( 28610988) Heart rate response to exercise ( 29769521) Heart rate response to recovery post exercise ( 29769521) Heart rate variability traits (pvRSA/HF) ( 28613276) Heart rate variability traits (RMSSD) ( 28613276) Heart rate variability traits (SDNN) ( 28613276) Resting heart rate ( 27798624) Weight ( 28552196)	Adult body size ( 32376654) Breast cancer ( 23535729) Coronary artery disease ( 29212778 33020668) Heel bone mineral density ( 30598549) LDL cholesterol ( 30275531) Logical memory (delayed recall) ( 29274321) Myocardial infarction ( 33532862)
Interacting Genes		25 interacting genes: COL17A1 CPSF6 DDIT4L GADD45G HNRNPA1 HNRNPUL1 KPRP LHX2 LNX2 N4BP2L2 POU6F2 PPP1R8 PRR22 PRR35 RBM42 RIMBP3 SF3B3 SNW1 SPDYE4 SRPK1 SRPK2 TCF4 THOC5 UFL1 WDR77	7 interacting genes: EXOSC8 HOXA1 LMO2 NAA38 PPIA PPIH PPIL1
Entrez ID		51645	10443
HPRD ID		03194	15119
Ensembl ID		ENSG00000137168	ENSG00000244754
Uniprot IDs		A0A024RCX8 Q9Y3C6	A0A024RDV2 B4DPY1 Q92802 Q9Y3H6
PDB IDs		1XWN 2K7N 2X7K 5MQF 5XJC 5YZG 5Z56 5Z57 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV 6ZYM
Enriched GO Terms of Interacting Partners?
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