DYNC2LI1 and RASGRP3

		DYNC2LI1	RASGRP3
Description		dynein cytoplasmic 2 light intermediate chain 1	RAS guanyl releasing protein 3
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Centrosome Cytoplasmic Dynein Complex Cytoplasmic Microtubule Cilium Axoneme Motile Cilium Ciliary Transition Zone Ciliary Basal Body Apical Part Of Cell Ciliary Tip	Plasma Membrane Integral Component Of Plasma Membrane Guanyl-nucleotide Exchange Factor Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Dynein Heavy Chain Binding	Guanyl-nucleotide Exchange Factor Activity GTPase Activator Activity Calcium Ion Binding Protein Binding Kinase Binding Diacylglycerol Binding Small GTPase Binding
	Biological Process	Determination Of Left/right Symmetry Intraciliary Retrograde Transport Intraciliary Transport Involved In Cilium Assembly Regulation Of Cilium Assembly	MAPK Cascade Small GTPase Mediated Signal Transduction Ras Protein Signal Transduction Regulation Of GTPase Activity
Pathways		Intraflagellar transport	Activation of RAS in B cells Activation of RAS in B cells RAF/MAP kinase cascade
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Hematocrit ( 32888494) Hemoglobin ( 32888494) Red blood cell count ( 32888494) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)	Albumin-globulin ratio ( 29403010) Bronchopulmonary dysplasia in preterm infants ( 30113228) Hypertension (young onset) ( 19421330) IgG response to Plasmodium falciparum antigens (GLURP, MSP2 FC27, MSP2 3D7) ( 26741287) Metabolite levels ( 23823483) Multiple system atrophy (pathologically confirmed) ( 27629089) Non-albumin protein levels ( 29403010) Non-response to antidepressants and depression ( 27622933) SjÃ¶gren's syndrome ( 24097067) Systemic lupus erythematosus ( 27399966 23273568 33272962 26663301 28714469 19838193)
Interacting Genes		4 interacting genes: DCDC2 DYNC2H1 ITGB1BP1 RASGRP3	12 interacting genes: APP DYNC2LI1 DYNLL2 GET1 HSD17B11 PIK3CA PRKACA PRKCB PRKCD PRKCE PRKCQ SULT1C2
Entrez ID		51626	25780
HPRD ID		13116	15213
Ensembl ID		ENSG00000138036	ENSG00000152689
Uniprot IDs		Q8TCX1	Q8IV61
PDB IDs		6RLB 6SC2
Enriched GO Terms of Interacting Partners?
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