IP6K2 and PLOD3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		IP6K2	PLOD3
Description		inositol hexakisphosphate kinase 2	procollagen-lysine,2-oxoglutarate 5-dioxygenase 3
Image		No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Cell Junction	Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Golgi Apparatus Trans-Golgi Network Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Inositol-1,3,4,5,6-pentakisphosphate Kinase Activity Inositol Hexakisphosphate Kinase Activity Inositol Heptakisphosphate Kinase Activity Inositol Hexakisphosphate 5-kinase Activity Protein Binding ATP Binding Kinase Activity Inositol 5-diphosphate Pentakisphosphate 5-kinase Activity Inositol Diphosphate Tetrakisphosphate Kinase Activity Flavonoid Binding	Iron Ion Binding Protein Binding Procollagen-lysine 5-dioxygenase Activity L-ascorbic Acid Binding Procollagen Glucosyltransferase Activity Procollagen Galactosyltransferase Activity
	Biological Process	Phosphate Ion Transport Phosphorylation Negative Regulation Of Cell Growth Inositol Phosphate Biosynthetic Process Positive Regulation Of Apoptotic Process Inositol Phosphate Metabolic Process Phosphatidylinositol Phosphate Biosynthetic Process Cellular Response To Flavonoid	In Utero Embryonic Development Endothelial Cell Morphogenesis Protein O-linked Glycosylation Protein Localization Peptidyl-lysine Hydroxylation Neural Tube Development Collagen Fibril Organization Cellular Response To Hormone Stimulus Collagen Metabolic Process Vasodilation Hydroxylysine Biosynthetic Process Epidermis Morphogenesis Lung Morphogenesis Basement Membrane Assembly
Pathways		Synthesis of IPs in the nucleus Interferon alpha/beta signaling	Collagen biosynthesis and modifying enzymes
Drugs			Ascorbic acid
Diseases
GWAS		Adult body size ( 32376654) Age at first birth ( 34211149) Apolipoprotein A1 levels ( 33730874) Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cognitive function ( 25644384) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Diastolic blood pressure ( 27841878) Eosinophil counts ( 32888494) Experiencing mood swings ( 29500382) Feeling fed-up ( 29500382) General cognitive ability ( 29844566) HDL cholesterol ( 30275531) Household income (MTAG) ( 31844048) Inflammatory bowel disease ( 28067908 23128233) Morning person ( 30696823) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Refractive error ( 32231278) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908 25082827) Waist circumference adjusted for body mass index ( 34021172)	Blood protein levels ( 30072576)
Interacting Genes		8 interacting genes: HSP90AA1 LNX2 MEOX2 PLOD3 PLSCR1 QRICH1 RBPMS ZBTB2	20 interacting genes: CCDC85B COIL COL17A1 CRIP3 DPPA2 EFHC2 EHMT2 FAM153A IP6K2 KCTD9 KHNYN L3MBTL3 LINC00839 NAB2 RAB3IP RALY RHOU RHOXF2 SORBS3 ZNF620
Entrez ID		51447	8985
HPRD ID		07380	04347
Ensembl ID		ENSG00000068745	ENSG00000106397
Uniprot IDs		A8K636 B2RCP4 Q9UHH9	O60568 Q9UG85
PDB IDs			6FXK 6FXM 6FXR 6FXT 6FXX 6FXY
Enriched GO Terms of Interacting Partners?
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