PDE4D and AKAP6

  • Number of citations of the paper that reports this interaction (PubMedID 11296225)
  • 139
  • Data Source:
  • HPRD (in vivo, in vitro)

PDE4D

AKAP6

Description phosphodiesterase 4D A-kinase anchoring protein 6
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
  • Age at first sexual intercourse ( 34211149)
  • Anorexia nervosa ( 21079607)
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Asthma ( 29273806)
  • Atrial fibrillation ( 30061737 29892015)
  • Bipolar disorder ( 31043756)
  • Body mass index ( 28892062 25673413 29273807 28448500)
  • Body mass index (joint analysis main effects and physical activity interaction) ( 28448500)
  • Body mass index and systole blood pressure (pairwise) ( 33619380)
  • Body mass index in physically active individuals ( 28448500)
  • Body size at age 10 ( 32376654)
  • Coffee consumption ( 31046077)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Cognitive function ( 25644384)
  • Creatine kinase levels ( 29403010)
  • Diisocyanate-induced asthma ( 25918132)
  • Economic and political preferences (environmentalism) ( 22566634)
  • Fasting blood insulin (BMI interaction) ( 22581228)
  • General cognitive ability ( 29844566)
  • Glioma ( 28346443)
  • HDL cholesterol levels ( 32203549)
  • Intelligence (MTAG) ( 29326435)
  • Night sleep phenotypes ( 27126917)
  • Non-glioblastoma glioma ( 28346443)
  • Photic sneeze reflex ( 27182965)
  • PR interval ( 32439900)
  • Refractive error ( 32231278)
  • Schizophrenia ( 28991256 30285260)
  • Spherical equivalent or myopia (age of diagnosis) ( 29808027)
  • Type 2 diabetes ( 30297969)
  • Type 2 diabetes or prostate cancer (pleiotropy) ( 33290408)
  • Walking pace ( 33128006)
Interacting Genes 29 interacting genes: ABL1 AKAP6 APP ARRB1 ARRB2 COIL CSNK1A1 FBXO7 FURIN FYN GOLGA8EP GOLGA8F GRB2 GSK3B HRAS LYN MAGEA6 MAPK1 MDM2 PAFAH1B1 PDE4DIP PIAS4 PIK3R1 PRKACA RACK1 SPTAN1 SRC TRAF1 TRIM23 19 interacting genes: BIRC5 CALM1 CDC5L DISC1 DTNBP1 FUT3 GEMIN2 MAGEA6 PABPN1 PDE4D PGC PPP2CA PRKAR2A PTPRM RYR1 RYR2 SLC8A1 SPTSSA SSTR1
Entrez ID 5144 9472
HPRD ID 02530 05257
Ensembl ID ENSG00000113448 ENSG00000151320
Uniprot IDs A0A140VJR0 Q08499 B2RP22 Q13023
PDB IDs 1E9K 1MKD 1OYN 1PTW 1Q9M 1TB7 1TBB 1XOM 1XON 1XOQ 1XOR 1Y2B 1Y2C 1Y2D 1Y2E 1Y2K 1ZKN 2FM0 2FM5 2PW3 2QYN 3G4G 3G4I 3G4K 3G4L 3G58 3IAD 3IAK 3K4S 3SL3 3SL4 3SL5 3SL6 3SL8 3V9B 4OGB 4W1O 4WCU 5K1I 5K32 5LBO 5TKB 5WH5 5WH6 5WQA 6AKR 6BOJ 6F6U 6F8R 6F8T 6F8U 6F8V 6F8W 6F8X 6FDC 6FDI 6FE7 6FEB 6FET 6FT0 6FTA 6FTW 6FW3 6HWO 6IAG 6IBF 6IM6 6IMB 6IMD 6IMI 6IMO 6IMR 6IMT 6IND 6INK 6INM 6KJZ 6KK0 6NJH 6NJI 6NJJ 6RCW 6ZBA 7CBQ
Enriched GO Terms of Interacting Partners?
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