SCAND1 and RNF186

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SCAND1	RNF186
Description		SCAN domain containing 1	ring finger protein 186
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Positive Regulation Of Transcription, DNA-templated	Protein K29-linked Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein Autoubiquitination Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Protein K63-linked Ubiquitination Protein Localization To Mitochondrion
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Hip circumference adjusted for BMI ( 25673412) Refractive error ( 32231278)	Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 28067908 20228799 19122664 23511034)
Interacting Genes		54 interacting genes: AGTRAP APH1A CALCOCO2 CCDC51 DGAT2L6 GOLGA6L9 GORASP2 KRT40 LHX4 MAPK3 MAPK8 MZF1 NDUFB5 NFE2 PGBD1 PICK1 PNMA1 POU2AF1 RER1 RNF186 RPRM SFT2D1 SHISA5 SLC17A9 TMEM207 TMEM239 TMEM95 TRIP6 TVP23A ZKSCAN3 ZKSCAN4 ZKSCAN7 ZNF165 ZNF174 ZNF202 ZNF213 ZNF24 ZNF263 ZNF394 ZNF396 ZNF397 ZNF446 ZNF449 ZNF483 ZNF496 ZSCAN12 ZSCAN16 ZSCAN18 ZSCAN20 ZSCAN21 ZSCAN22 ZSCAN23 ZSCAN25 ZSCAN32	8 interacting genes: EPHB2 EPHB3 HIVEP1 PBX3 SCAND1 SESN2 UBE2D2 UBE2H
Entrez ID		51282	54546
HPRD ID		15298	07885
Ensembl ID		ENSG00000171222	ENSG00000178828
Uniprot IDs		H0UIA5 P57086 Q9NZG6	Q9NXI6
PDB IDs
Enriched GO Terms of Interacting Partners?
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