KLF3 and LHX6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KLF3	LHX6
Description		Kruppel like factor 3	LIM homeobox 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleoplasm	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Cellular Response To Peptide	Regulation Of Transcription By RNA Polymerase II Cerebral Cortex Radially Oriented Cell Migration Cerebral Cortex Tangential Migration Cerebral Cortex GABAergic Interneuron Migration Forebrain Neuron Development Neuron Differentiation Cell Maturation
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31959851) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 23850713) Endometriosis or endometrial cancer (pleiotropy) ( 29608257) Eosinophil counts ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Hand grip strength ( 29691431) Helicobacter pylori serologic status ( 23652523) Lymphocyte counts ( 32888494 27863252) Lymphocyte percentage of white cells ( 32888494) Mean platelet volume ( 32888494) Monocyte percentage of white cells ( 32888494) Multiple sclerosis ( 31604244) Neutrophil percentage of granulocytes ( 27863252) Neutrophil percentage of white cells ( 32888494) Relative brain age ( 34098431) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Subcortical volume (MOSTest) ( 32665545) Sum eosinophil basophil counts ( 27863252) Type 1 diabetes ( 34127860) White blood cell count ( 32888494 27863252)	Malaria ( 31844061)
Interacting Genes		14 interacting genes: CTBP1 CTBP2 DVL3 EHMT2 FHL3 KDM1A LHX6 LHX8 LSM3 OTX2 PIAS1 SUV39H2 TRAF2 UBE2I	9 interacting genes: CPNE1 FAM90A1 FIGLA KLF3 LDB1 NRF1 ROR2 ZNF138 ZNF76
Entrez ID		51274	26468
HPRD ID		13920	10498
Ensembl ID		ENSG00000109787	ENSG00000106852
Uniprot IDs		P57682	A0A024R852 Q9UPM6
PDB IDs
Enriched GO Terms of Interacting Partners?
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