CLEC1A and CERS4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CLEC1A	CERS4
Description		C-type lectin domain family 1 member A	ceramide synthase 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Intracellular Anatomical Structure Integral Component Of Plasma Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding Carbohydrate Binding	DNA Binding Protein Binding N-acyltransferase Activity Sphingosine N-acyltransferase Activity
	Biological Process	Defense Response Cell Surface Receptor Signaling Pathway	Sphingolipid Biosynthetic Process Ceramide Biosynthetic Process
Pathways			Sphingolipid de novo biosynthesis
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)	Macular telangiectasia type 2 ( 33654266) Mean reticulocyte volume ( 32888494) Metabolite levels ( 31628463) Red cell distribution width ( 32888494) Refractive error ( 32231278) Serum metabolite levels ( 33031748) Serum metabolite ratios in chronic kidney disease ( 29545352) Sphingolipid levels ( 26068415) Sphingomyelin levels ( 31551469) Thyroid stimulating hormone levels ( 30367059 32769997) Very long-chain saturated fatty acid levels (fatty acid 24:0) ( 25378659)
Interacting Genes		14 interacting genes: CERS4 CLEC12A FFAR2 FNDC9 GJA8 GPR152 GPX8 LMNA LRRC25 LRRC4C MRPS18B RNF19B STX1A TRAM1L1	47 interacting genes: - C1QL4 CCL4L2 CLEC1A COL4A5 CTXN3 CXCL16 CYB5R3 EMD FATE1 FCER1G FXYD6 FXYD6-FXYD2 GPR151 IER3IP1 IGFBP5 ITGAM JAGN1 LHFPL5 MS4A1 NAT8 NEU1 PLP2 PNLIPRP1 PTPN9 SCAMP5 SCD SERF1A SERF1B SERP2 SLC13A4 SLC29A2 SLC35A1 SLC35F6 SLC7A1 SMIM11 STX7 STX8 TEX264 TMEM119 TMEM176A TMEM254 TMEM72 TOMM6 TSPO2 UPK1B VAMP2
Entrez ID		51267	79603
HPRD ID		09489	13962
Ensembl ID		ENSG00000150048	ENSG00000090661
Uniprot IDs		B3KRP6 B4DV89 E7ESV9 E9PFB4 Q8NC01	Q53HF9 Q9HA82
PDB IDs
Enriched GO Terms of Interacting Partners?
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