TBC1D7 and SH3GLB2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TBC1D7	SH3GLB2
Description		TBC1 domain family member 7	SH3 domain containing GRB2 like, endophilin B2
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoplasmic Vesicle Ciliary Basal Body	Nucleoplasm Cytoplasm Cytosol
	Molecular Function	GTPase Activator Activity Protein Binding Small GTPase Binding	Protein Binding Identical Protein Binding Cadherin Binding
	Biological Process	Positive Regulation Of Protein Ubiquitination Negative Regulation Of TOR Signaling Positive Regulation Of GTPase Activity Response To Growth Factor Activation Of GTPase Activity Negative Regulation Of Cilium Assembly
Pathways		TBC/RABGAPs
Drugs
Diseases
GWAS		Migraine ( 23793025) Migraine without aura ( 23793025)	Blood metabolite levels ( 26401656) Serum metabolite concentrations in chronic kidney disease ( 33838163)
Interacting Genes		30 interacting genes: AKT1 ALOX5 APP BAG4 BLZF1 GABARAPL1 HOOK1 IKBKG INCA1 KEAP1 KRT19 KRT35 LDOC1 LNX2 LZTS1 LZTS2 MAP1LC3A MIPOL1 MMADHC NEDD4 NEDD4L PICK1 RPGRIP1 SH3GLB2 SSNA1 TRAF4 TRIM62 TSC1 XPA YWHAZ	38 interacting genes: CCDC158 CCND3 CDKN2D CNOT7 EFHC1 EXOSC1 EXOSC5 FHL3 FXR1 GAA GADD45G GIT2 GOLGA2 KDM1A KRTAP10-1 KRTAP10-8 KRTAP4-5 KRTAP5-11 KRTAP9-3 LGALS14 LNX2 LSM3 MAGEA1 MORF4L1 NMI NTAQ1 NXF1 OGT PICK1 SH3GLB1 SH3KBP1 SREK1 STX4 TBC1D7 TEX11 TRAF1 TSG101 YES1
Entrez ID		51256	56904
HPRD ID		18165	15334
Ensembl ID		ENSG00000145979	ENSG00000148341
Uniprot IDs		A0A024QZX0 A0A024R011 Q5JPB9 Q9P0N9 U3KPY5	A0A024R896 B7ZC38 Q9NR46
PDB IDs		3QWL 4Z6Y 5EJC 5ULO 7DL2
Enriched GO Terms of Interacting Partners?
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