ELOA2 and CHD2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ELOA2	CHD2
Description		elongin A2	chromodomain helicase DNA binding protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Elongin Complex	Nucleus
	Molecular Function	Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding DNA Helicase Activity RNA Binding Protein Binding ATP Binding ATP Hydrolysis Activity Histone Binding ATP-dependent Chromatin Remodeler Activity
	Biological Process	Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Regulation Of DNA-templated Transcription, Elongation	Chromatin Organization Regulation Of Transcription By RNA Polymerase II Cellular Response To DNA Damage Stimulus Muscle Organ Development DNA Duplex Unwinding Hematopoietic Stem Cell Differentiation
Pathways		Formation of RNA Pol II elongation complex Formation of HIV elongation complex in the absence of HIV Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS			Adolescent idiopathic scoliosis ( 30395268) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Daytime nap ( 33568662) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483) Pulse pressure ( 30224653)
Interacting Genes		23 interacting genes: CALCOCO2 CBX5 CDK6 CEP70 CHD2 COIL DVL2 ELOB ELOC HSF2BP KRTAP4-12 KXD1 NKAPD1 RNPS1 SOHLH2 SREK1IP1 TRAF2 TRIM37 ZBTB43 ZCCHC10 ZNF138 ZNF165 ZNF23	12 interacting genes: BEND7 ELOA2 MEOX2 MID2 NR2F2 SRPK2 TEKT1 THAP1 TRIM41 TRIM54 TULP3 ZNF398
Entrez ID		51224	1106
HPRD ID		18169	03669
Ensembl ID		ENSG00000206181	ENSG00000173575
Uniprot IDs		Q8IYF1	O14647
PDB IDs
Enriched GO Terms of Interacting Partners?
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