PLEKHO1 and CDC42SE1

		PLEKHO1	CDC42SE1
Description		pleckstrin homology domain containing O1	CDC42 small effector 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Ruffle Membrane Muscle Cell Projection Membrane	Cytoplasm Cytoskeleton Plasma Membrane Cell Junction
	Molecular Function	Protein Binding	GTPase Inhibitor Activity Small GTPase Binding
	Biological Process	Myoblast Fusion Regulation Of Cell Shape Myoblast Migration Lamellipodium Morphogenesis Regulation Of Myoblast Fusion	Phagocytosis Signal Transduction Regulation Of Cell Shape Regulation Of Rho Protein Signal Transduction Negative Regulation Of Catalytic Activity
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		40 interacting genes: ADAM33 ADAMTSL4 AKT1 AKT2 BNIP2 BRICD5 C10orf88 C1orf56 C4orf3 CDC42SE1 CEP19 COL8A2 CSNK2A1 CYP4F2 DNAJB1 FLNB GOLPH3L IFI35 LRP10 MMD NAPB OGT PSMC5 RPRD2 RPS20 SMAD5 SMG5 SMURF1 SYT11 THSD7B TMEM218 TNF TRAF3IP3 TRAF6 TRAM1L1 TSPAN33 TSPO2 USP7 VAMP3 ZFPL1	7 interacting genes: CDC42 DAPK1 OTUD7B PLEKHO1 RAC1 SLC44A2 SNCA
Entrez ID		51177	56882
HPRD ID		12217	16694
Ensembl ID		ENSG00000023902	ENSG00000197622
Uniprot IDs		Q53GL0 Q5T4P9	Q9NRR8
PDB IDs		3AA1
Enriched GO Terms of Interacting Partners?
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