DYNC1LI1 and TRIM71

		DYNC1LI1	TRIM71
Description		dynein cytoplasmic 1 light intermediate chain 1	tripartite motif containing 71
Image			No pdb structure
GO Annotations	Cellular Component	Kinetochore Spindle Pole Centrosome Cytosol Cytoplasmic Dynein Complex Microtubule Plasma Membrane Membrane Secretory Granule Membrane Ficolin-1-rich Granule Membrane	P-body
	Molecular Function	RNA Binding Protein Binding ATP Binding GTP Binding GDP Binding Dynein Heavy Chain Binding	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Translation Repressor Activity MiRNA Binding Ubiquitin Protein Ligase Activity
	Biological Process	Microtubule Cytoskeleton Organization Microtubule-based Movement Cell Cycle Cell Division Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint	G1/S Transition Of Mitotic Cell Cycle Protein Polyubiquitination Neural Tube Closure Fibroblast Growth Factor Receptor Signaling Pathway MiRNA Metabolic Process Posttranscriptional Regulation Of Gene Expression Negative Regulation Of Translation Neural Tube Development Production Of MiRNAs Involved In Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein Autoubiquitination Regulation Of Gene Silencing By MiRNA 3'-UTR-mediated MRNA Destabilization Stem Cell Proliferation Regulation Of Neural Precursor Cell Proliferation Positive Regulation Of Gene Silencing By MiRNA
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand RHO GTPases Activate Formins Neutrophil degranulation COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase HCMV Early Events Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Bitter taste perception (6-n-propylthiouracil) in obesity with metabolic syndrome ( 31005965) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Low density lipoprotein cholesterol levels ( 33339817)	Asthma ( 31959851) Asthma (childhood onset) ( 31036433) Heel bone mineral density ( 30598549) Metabolite levels ( 23823483) Multiple sclerosis ( 31604244) Pulmonary function ( 21946350) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		14 interacting genes: BRCA2 CMTM6 CMTM7 FBXL2 GPD1L IKBKG NOP56 NUP85 OGT PGAM2 RAB4A REL SUSD5 TRIM71	13 interacting genes: CDKN1A DYNC1LI1 LIN28B MIR1-1 MIR1-2 MIR100 MIR155 MIR15A MIR18B MIR25 MIR29A MIR29B1 MIRLET7F2
Entrez ID		51143	131405
HPRD ID		10917	19029
Ensembl ID		ENSG00000144635	ENSG00000206557
Uniprot IDs		E9PHI6 Q9Y6G9	Q2Q1W2
PDB IDs		6B9H 6PSD 6PSE
Enriched GO Terms of Interacting Partners?
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